Results 31 to 40 of about 387,273 (262)

Attacks and countermeasures on federated learning via historical knowledge modeling

open access: yesJournal of King Saud University: Computer and Information Sciences
Federated learning has emerged as a promising paradigm for privacy-preserving multi-source data fusion. However, its distributed nature makes it vulnerable to poisoning attacks.
Songsong Zhang   +4 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Incorporating Gaming in Software Engineering Projects: Case of RMU Monopoly [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2009
A major challenge in engineering education is retaining student interest in the engineering discipline. Active student involvement in engineering projects is one way of retaining student interest.
Sushil Acharya, David Burke
doaj  

An Assessment of Educational Benefits from the OpenOrbiter Space Program

open access: yesEducation Sciences, 2013
This paper analyzes the educational impact of the OpenOrbiter Small Spacecraft Development Initiative, a CubeSat development program underway at the University of North Dakota.
David Whalen, Jeremy Straub
doaj   +1 more source

An Approach for Evolving Transformation Sequences Using Hybrid Genetic Algorithms

open access: yesInternational Journal of Computational Intelligence Systems, 2020
The digital transformation revolution has been crawling toward almost all aspects of our lives. One form of the digital transformation revolution appears in the transformation of our routine everyday tasks into computer executable programs in the form of
Ahmed Maghawry   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Instructional Design for Engineering System Based Software Cycle Methodology (IDSCM) [PDF]

open access: yesEngineering and Technology Journal, 2019
An instructional program has been prepared depending on instructional design concepts to present concepts and information of an engineering system. The design and construction of an instructional program have done by using analysis design implementation ...
Iman Kareem
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

A Method for Considering Error Propagation in Reliability Estimation of Component-Based Software Systems [PDF]

open access: yesInternational Journal of Mathematical, Engineering and Management Sciences, 2019
Component-based software engineering has proved itself as a strong pillar in software engineering community. Large number of factors are involved in the success of software product developed using Component-based software engineering, for instance ...
Preeti Malik, Lata Nautiyal, Mangey Ram
doaj   +1 more source

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