Results 31 to 40 of about 1,633,242 (297)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Evaluating User Experience E-Commerce Platform Using Hassenzahl Framework
International Journal of Applied Sciences and Smart TechnologiesThe Hassenzahl framework of UX provides an approach in measuring user experience of a product which covers such the following aspects : be goals, do goals, and motor goals.
Stevanus Wisnu Wijaya +1 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Attacks and countermeasures on federated learning via historical knowledge modeling
Journal of King Saud University: Computer and Information SciencesFederated learning has emerged as a promising paradigm for privacy-preserving multi-source data fusion. However, its distributed nature makes it vulnerable to poisoning attacks.
Songsong Zhang +4 more
doaj +1 more source
An Approach for Evolving Transformation Sequences Using Hybrid Genetic Algorithms
International Journal of Computational Intelligence Systems, 2020 The digital transformation revolution has been crawling toward almost all aspects of our lives. One form of the digital transformation revolution appears in the transformation of our routine everyday tasks into computer executable programs in the form of
Ahmed Maghawry +3 more
doaj +1 more source
Instructional Design for Engineering System Based Software Cycle Methodology (IDSCM) [PDF]
Engineering and Technology Journal, 2019 An instructional program has been prepared depending on instructional design concepts to present concepts and information of an engineering system. The design and construction of an instructional program have done by using analysis design implementation ...
Iman Kareem
doaj +1 more source
The Java system dependence graph [PDF]
, 2003 The Program Dependence Graph was introduced by Ottenstein and Ottenstein in 1984 [14]. It was suggested to be a suitable internal program representation for monolithic programs, for the purpose of carrying out certain software engineering operations such
Roper, M., Walkinshaw, N., Wood, M.
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An Assessment of Educational Benefits from the OpenOrbiter Space Program
Education Sciences, 2013 This paper analyzes the educational impact of the OpenOrbiter Small Spacecraft Development Initiative, a CubeSat development program underway at the University of North Dakota.
David Whalen, Jeremy Straub
doaj +1 more source
A Method for Considering Error Propagation in Reliability Estimation of Component-Based Software Systems [PDF]
International Journal of Mathematical, Engineering and Management Sciences, 2019 Component-based software engineering has proved itself as a strong pillar in software engineering community. Large number of factors are involved in the success of software product developed using Component-based software engineering, for instance ...
Preeti Malik, Lata Nautiyal, Mangey Ram
doaj +1 more source