Results 91 to 100 of about 6,217,824 (300)

A framework for the simulation of structural software evolution [PDF]

open access: yes, 2008
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2008 ACM.As functionality is added to an aging piece of software, its original design and structure will tend to erode.
Stopford, B   +3 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Optimized Differential Evolution Algorithm for Software Testing

open access: yesInternational Journal of Computational Intelligence Systems, 2018
Differential evolution (DE) algorithms for software testing usually exhibited limited performance and stability owing to possible premature-convergence-related aging during evolution processes.
Xiaodong Gou   +4 more
doaj   +1 more source

Understanding and simulating software evolution [PDF]

open access: yes2013 35th International Conference on Software Engineering (ICSE), 2013
The important roles of software in modern life have prompted people to study software evolution.This dissertation takes a scientific perspective to model the dynamics of software evolution, and verify the model by simulation.Empirical studies of software evolution have discovered many emergent phenomena, such as the power law distributions in different
openaire   +2 more sources

Architecture-Based Software Evolution: A Multi-Dimensional Approach [PDF]

open access: yes, 2007
Software Evolution is unavoidable because software systems are subject to continuous change, continuing growth and increasing complexity. As software systems become mission-critical and large in size, the complexity in software development is now ...
Wang, Huan
core   +1 more source

Increasing efficiency and effectiveness of software product line evolution - an infrastructure on top of configuration management

open access: yes, 2022
S.47-56Software Product Line Engineering entails the strategic development of software assets that are to be reused many times across the members of a product line. Assuring that the investment in reuse holds over time is an important requirement in this
Anastasopoulos, Michalis
core   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

A software system for safety supervision of coal mining in China: Adapted evolutionary jungle model, and simulation and analysis of the co-evolution process of the interaction between supervision agents and the enterprise agents, and how the stable coexistence equilibrium point can be reached

open access: yes, 2017
A software system for modelling and simulating safety supervision of coal mining in China: Adapted evolutionary jungle model, and simulation and analysis of the co-evolution process of the interaction between supervision agents and the enterprise agents,
Huang, D., Li, Shuliang
core  

Software evolution visualization: A systematic mapping study

open access: yes, 2022
S.1860-1883Background: Software evolution is an important topic in software engineering. It generally deals with large amounts of data, as one must look at whole project histories as opposed to their current snapshot.
Novais, R.L.   +4 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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