Results 61 to 70 of about 131,766 (331)

Reliability prediction in model driven development [PDF]

open access: yes, 2005
Evaluating the implications of an architecture design early in the software development lifecycle is important in order to reduce costs of development.
Rodrigues, G.N.   +2 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Improved prediction of software defect: A particle swarm optimization based ELM approach

open access: yese-Prime: Advances in Electrical Engineering, Electronics and Energy
Ensuring software reliability before deployment is essential, as human errors during development are a major source of defects. Identifying and resolving these issues at an early stage can greatly minimize their impact.
Debasish Pradhan, Debendra Muduli
doaj   +1 more source

Evaluating the Assessment of Software Fault-Freeness [PDF]

open access: yes, 2014
We propose to validate experimentally a theory of software certification that proceeds from assessment of confidence in fault-freeness (due to standards) to conservative prediction of failure-free ...
Littlewood, B., Rushby, J., Strigini, L.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Rough Noise-Filtered Easy Ensemble for Software Fault Prediction

open access: yesIEEE Access, 2018
Software fault prediction is the very important research topic for software quality assurance. Data-driven approaches provide robust mechanisms to deal with software fault prediction. However, the prediction performance of the model highly depends on the
Saman Riaz, Ali Arshad, Licheng Jiao
doaj   +1 more source

Optimal Release Time Estimation of Software System using Box-Cox Transformation and Neural Network [PDF]

open access: yesInternational Journal of Mathematical, Engineering and Management Sciences, 2018
The determination of the software release time for a new software product is the most critical issue for designing and controlling software development processes.
Momotaz Begum, Tadashi Dohi
doaj   +1 more source

Feature Selection Using Golden Jackal Optimization for Software Fault Prediction

open access: yesMathematics, 2023
A program’s bug, fault, or mistake that results in unintended results is known as a software defect or fault. Software flaws are programming errors due to mistakes in the requirements, architecture, or source code. Finding and fixing bugs as soon as they
Himansu Das   +5 more
doaj   +1 more source

Fault Detection Effectiveness of Metamorphic Relations Developed for Testing Supervised Classifiers

open access: yes, 2019
In machine learning, supervised classifiers are used to obtain predictions for unlabeled data by inferring prediction functions using labeled data. Supervised classifiers are widely applied in domains such as computational biology, computational physics ...
Kanewala, Upulee, Saha, Prashanta
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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