Results 141 to 150 of about 7,627 (199)

Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez   +295 more
wiley   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

open access: yesArthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz   +13 more
wiley   +1 more source

Integration of the arts and biomedical engineering in innovative interdisciplinary anatomy education: The synthetic anatomy module

open access: yesAnatomical Sciences Education, EarlyView.
Abstract The intersection of science and art has historically fostered innovation, yet the integration of creative arts into anatomy education remains limited. The Synthetic Anatomy module was designed to bridge anatomy teaching with creative design for bioscience and biomedical engineering students. This study evaluates the module's educational impact
Mandeep Gill Sagoo   +6 more
wiley   +1 more source

More‐than‐gender? Moving beyond gendered expectations of divergent learners in early childhood education

open access: yesBritish Educational Research Journal, EarlyView.
Abstract In this paper, we explore how neurodivergent ways of being in early education are often gendered. The intersectionalities of gender and neurodivergence often lead to fixed expectations that perpetuate binary interpretations, pathologisations, missed diagnoses and a lack of curated support.
Ruth Churchill Dower, Hannah Hogarth
wiley   +1 more source

The epistemic ceiling: Veteran practitioners' perspectives on primary qualification entry standards for teaching secondary mathematics in Scotland

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This paper presents an exploratory analysis of contemporary curricular and professional qualification policies in the Scottish education system, focusing on minimum qualification thresholds for mathematics teaching. The study examines how veteran secondary mathematics practitioners perceive the structural and pedagogical implications of using ...
Paul Argyle McDonald
wiley   +1 more source

Development, validation, and biomechanical evaluation of a high-fidelity finite element model of the forearm musculoskeletal system​. [PDF]

open access: yesBMC Musculoskelet Disord
Shang RG   +9 more
europepmc   +1 more source

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