Results 151 to 160 of about 84,866 (259)

The Missing Link: Connecting Cultivation Conditions and Refolding Performance via Inclusion Body Biophysical Properties

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Inclusion bodies (IBs) frequently form during the expression of heterologous proteins in Escherichia coli and are therefore important in pharmaceutical production. While it is accepted that cultivation conditions affect cultivation performance, the link to refolding performance remains unexplored. This study proposes that this interplay relies,
Matthias Rüdt, Aymerick Bussien, Joan Cortada‐Garcia, Holger Morschett, Hauke Holm, Chiara Mazzucchelli, Karlheinz Flicker   +6 more
wiley   +1 more source

Variation of and associations with the depth and evenness of sequencing coverage in archived plastid genomes. [PDF]

Sci Rep
Jenke N, Smith GM, Magar BT, Gruenstaeudl M.   +3 more
europepmc   +1 more source

MAD-Onto: an ontology design for mobile app development. [PDF]

Front Artif Intell
Abu-Salih B, Al-Tawil M, Khoury A, Al-Qudah DA, Abu Zaid I, Alabdale M, Azar D.   +6 more
europepmc   +1 more source

ABCC11 Earwax Trait and Genotype Are Suitable Tools for Introductory Labs to Learn Genetics and Molecular Techniques

Biochemistry and Molecular Biology Education, EarlyView.
ABSTRACT Professional experiments in genetic research usually start in a class at university. However, interest in genetic research techniques from an early age is essential. We have continuously performed a short genetic experimental course for high school students using a simple molecular experiment and computer‐based learning for Mendelian ...
Tohru Ohta, Rie Takai, Akiko Yoshida, Durga Paudel, Sarita Giri, Takao Kitagawa, Toshiya Arakawa, Yasuhiro Kuramitsu, Tomoharu Tokutomi   +8 more
wiley   +1 more source

Proteome-wide prediction of the mode of inheritance and molecular mechanisms underlying genetic diseases using structural interactomics. [PDF]

iScience
Saadat A, Fellay J.
europepmc   +1 more source

Single‐Ion Conductive Bacterial Cellulose Membrane Towards High Performance Lithium‐Oxygen Batteries

Battery Energy, EarlyView.
Bacterial cellulose (BC) is a natural polymer with ultrafine nanofibrous network. BC membrane has excellent affinity to organic electrolyte, high ionic conductivity and inherent ion selectivity, which can transfer lithium ions and suppress the shuttling of anions across the membrane, available for iodide‐assisted lithium‐oxygen batteries (LOBs ...
Aqiang Wu, Mingxing Wang, Yaming Pang, Xinyu Li, Xiangqun Zhuge, Zhihong Luo, Guogang Ren, Kun Luo, Yurong Ren, Dan Liu, Weiwei Lei, Jianwei Lu   +11 more
wiley   +1 more source

Population data of 23 Y chromosome STR loci for Kyrgyz population from Kyrgyzstan. [PDF]

Data Brief
Isakova Z, Bukayev A, Irsaliev M, Sabitov Z, Zhabagin M.   +4 more
europepmc   +1 more source

Rotenoids from the Roots of Vicia faba L. (Fabaceae): Structural Characterization, Cytotoxic Effects, and Molecular Docking

Chemistry &Biodiversity, EarlyView.
ABSTRACT The chemical study of the ethanolic extract from the roots of Vicia faba led to the isolation of two isoflavonoids, alfalone and 8‐O‐methylretusine, as well as a mixture of rotenoids, including clitoriacetal and clitoriacetal B, the latter of which is reported for the first time.
Victor Menezes Sipoloni, João Victor Silva‐Silva, Elthon G. Ferreira, Eric Yoshitaka Lee, João Marcos Batista Junior, Miriam Uemi, Lívia Soman de Medeiros, Paula C. Jimenez, Thiago A. M. Veiga   +8 more
wiley   +1 more source

Genetic linkage mapping in Megathyrsus maximus (Jacq.) with multiple dosage markers. [PDF]

G3 (Bethesda)
Gesteira GS, Ferreira GC, Mollinari M, Santos MF, Jank L, Vilela MM, Raposo A, Chiari L, Zeng ZB, Garcia AAF.   +9 more
europepmc   +1 more source

Dominant‐Negative Effects of p53 R337 Variants in Li–Fraumeni Syndrome: Impact on Tetramer Formation and Transcriptional Activity

ChemBioChem, EarlyView.
Hetero‐tetramer dysfunction: Li–Fraumeni syndrome (LFS) is a hereditary cancer predisposition caused by mutations in the TP53 gene encoding the tumor suppressor p53. It is shown that p53 variants R337C and R337H, found in LFS, impair wild‐type (WT) p53 function by forming heterotetramers with reduced transcriptional activity.
Rui Kamada, Shuya Sakaguchi, Madoka Kanno, Takaaki Ozawa, Natsumi Nakagawa, James G. Omichinski, Kazuyasu Sakaguchi   +6 more
wiley   +1 more source