Results 161 to 170 of about 84,866 (259)

Digenic variant interpretation with hypothesis-driven explainable AI. [PDF]

NAR Genom Bioinform
De Paoli F, Nicora G, Berardelli S, Gazzo A, Bellazzi R, Magni P, Rizzo E, Limongelli I, Zucca S.   +8 more
europepmc   +1 more source

Hydrogen‐Deuterium Exchange Defines Ligand‐Induced Conformational Changes to the Class III Biotin Protein Ligase from Saccharomyces cerevisiae

ChemBioChem, EarlyView.
Hydrogen‐deuterium exchange mass spectrometry validated AlphaFold structural prediction of the class III biotin protein ligase (BPL) from Saccharomyces cerevisiae, and revealed a structured domain in the N‐terminal extension characteristic to this class of BPL.
Louise M. Sternicki, Tara L. Pukala, Kamila J. Pacholarz, Perdita Barran, Grant W. Booker, Steven W. Polyak, Kate L. Wegener   +6 more
wiley   +1 more source

Integrative Machine Learning Approaches for Identifying Loci Associated with Anthracnose Resistance in Strawberry. [PDF]

Plants (Basel)
Jang YJ, Yun D, Shin W, Goo C, Song CM, Han K, Kim S, Kim DS, Lee S, Oh Y.   +9 more
europepmc   +1 more source

Biomimetic and Compressible Wood Phase Change Gel With Hierarchically Aligned Lamellar Structure for Controlled Thermal Management

Carbon Energy, EarlyView.
Inspired by skeletal muscle thermogenesis, a wood phase change gel exhibiting mechano‐controlled heat release is developed. Under compression, the wood phase change gel overcomes its energy barrier, inducing its phase change from supercooling to crystallization and raising its overall temperature by around 5°C.
Jiazuo Zhou, Yifan Liu, Xinbei Jia, Yudong Li, Xiaohan Sun, Xinyao Ji, Yuan Yu, Taikun Yao, Zhuoer Li, Jian Li, Haiyue Yang, Yao Xiao, Wentao Gan, Chengyu Wang   +13 more
wiley   +1 more source

Feature selection using a multi-strategy improved parrot optimization algorithm in software defect prediction. [PDF]

PeerJ Comput Sci
Fei Q, Yin G, Sun Z.
europepmc   +1 more source

Walking Capacity in Children With Ataxia Telangiectasia From the Global Ataxia Telangiectasia Family Data Platform

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Walking capacity declines prematurely in individuals with ataxia telangiectasia. However, granular data on walking capacity loss in ataxia telangiectasia are scarce. In this large cross‐sectional cohort, we describe age‐related walking capacity loss reported by participants and compare categories of a subjective walking capacity ...
Biljana Horn, Alex Smith, Jennifer Thornton, Tara Symonds, Maureen Roden, Dirk Thye, William P. Whitehouse   +6 more
wiley   +1 more source

Slit tube responses and rock fracture characteristics in slit charge blasting under high in situ stress

Deep Underground Science and Engineering, EarlyView.
In this article, the finite element method‐smoothed particle hydrodynamics adaptive coupling algorithm is applied to numerically simulate and analyze the dynamic response of the slit tube and the crack propagation under high in situ stress. The dynamic response of the slit tube mainly exhibits radial response in the vertical direction of the slit and ...
Zhe Sui, Liyun Yang, Lijun Wu, Chenxi Ding   +3 more
wiley   +1 more source

Features extraction and fusion by attention mechanism for software defect prediction. [PDF]

PLoS One
Qiu S, E B, He J.
europepmc   +1 more source

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

Developmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu, Katja R. MacCharles, Kenneth Kin Lam Wong, Joy M. Richman, Esther M. Verheyen   +4 more
wiley   +1 more source

Adaptive multi-view learning method for enhanced drug repurposing using chemical-induced transcriptional profiles, knowledge graphs, and large language models. [PDF]

J Pharm Anal
Yan Y, Yang Y, Tong Z, Wang Y, Yang F, Pan Z, Liu C, Bai M, Xie Y, Li Y, Shu K, Li Y.   +11 more
europepmc   +1 more source