The art of software systems development: Reliability, Availability, Maintainability, Performance (RAMP) [PDF]
, 2013 Mohammad Malkawi
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Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
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A Code Refactoring Dataset and Its Assessment Regarding Software Maintainability [PDF]
, 2016 István Kádár +3 more
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Hierarchy of concepts and models for creating and maintaining software throughout the life cycle
, 2021 В.П. Хранилов +3 more
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A STUDY OF QUALITY IN THE PROCESS OF SOFTWARE PRODUCT DEVELOPMENT ACCORDING TO MAINTAINABILITY AND REUSABILITY [PDF]
Our research indicates the modality by which algorithm modifications imply intervention in modules where expressions are evaluated or selections of elements are performed, the conclusion being the fact that in order to design robust software, a clear ...
Andy STEFĂNESCU +2 more
core
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
The Scalability-Efficiency/Maintainability-Portability Trade-Off in Simulation Software Engineering: Examples and a Preliminary Systematic Literature Review [PDF]
, 2016 Dirk Pflüger +7 more
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How do Library Maintainers Refactor to Secure Software? A Study of Maven Releases
, 2021 Anonymous
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source