Results 51 to 60 of about 49,213 (322)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Code Smell Detection Using Ensemble Machine Learning Algorithms
Applied Sciences, 2022 Code smells are the result of not following software engineering principles during software development, especially in the design and coding phase. It leads to low maintainability.
Seema Dewangan +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Software Design Criteria for Maintainability [PDF]
, 1995 One of the current issues in the software engineering community is related to problems of software maintenance. It is a common belief that these problems are caused by bad software design and poor maintenance practices.
Deraman, Aziz, P. J., Layzell
core
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
SENSITIVITY-BASED LINEAR LEARNING METHOD AND EXTREME LEARNING MACHINES COMPARED FOR SOFTWARE MAINTAINABILITY PREDICTION OF OBJECT-ORIENTED SOFTWARE SYSTEMS [PDF]
ICTACT Journal on Soft Computing, 2013 This paper presented two maintainability prediction models that are developed and compared for object-oriented software systems based on the recently introduced learning algorithm called Sensitivity Based Linear Learning Method (SBLLM) and extreme ...
Sunday Olusanya Olatunji
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
PENGUKURAN KUALITAS WEBSITE PENGURUS CABANG NU DEPOK MENGGUNAKAN SOFTWARE METRIC
Jurnal Sisfokom, 2021 Website Pengurus Cabang Nahdlatul Ulama (PCNU) Depok dibuat sebagai sarana penyimpanan dan pengelolaan data dalam organisasi tersebut. Penelitian ini bertujuan untuk mengukur kualitas website PCNU Depok dilihat dari maintainability, flexibility dan ...
Ryan Aji Wijaya, Karmilasari
doaj +1 more source
Measuring the Quality of Machine Learning and Optimization Frameworks [PDF]
, 2018 Software frameworks are daily and extensively used in research, both for fundamental studies and applications. Researchers usually trust in the quality of these frameworks without any evidence that they are correctly build, indeed they could contain some
Alba-Torres, Enrique +2 more
core
Why Modern Open Source Projects Fail
, 2017 Open source is experiencing a renaissance period, due to the appearance of modern platforms and workflows for developing and maintaining public code. As a result, developers are creating open source software at speeds never seen before.
Androutsellis-Theotokis Stephanos +5 more
core +1 more source