Results 51 to 60 of about 2,544 (263)

Decision tree based code smell prioritization evaluation

open access: yes上海师范大学学报. 自然科学版, 2022
Based on the prioritization method of developer-driven code smell, combining with the optimization decision tree algorithm, a model was built to rank the refactoring priority of code smell for developers, which was evaluated in the empirical study.
GUO Di, WU Haitao
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Documentation as Code in Automotive System/Software Engineering

open access: yesElektronika ir Elektrotechnika, 2023
Documentation as Code (DaC) is an approach that applies the principles of software development to the production of technical documentation. Using modern tools, DaC enables software engineers to treat documentation as a first-class citizen in the ...
Momcilo V. Krunic
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Complexity Metrics Suite for Cascading Style Sheets

open access: yesComputers, 2019
We perform a theoretical and empirical analysis of a set of Cascading Style Sheets (CSS) document complexity metrics. The metrics are validated using a practical framework that demonstrates their viability. The theoretical analysis is performed using the
Adewole Adewumi   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Maintaining Configurations of Evolving Software Systems [PDF]

open access: yesIEEE Transactions on Software Engineering, 1987
Software configuration management ( SCM) is an emerging discipline. An important aspect of realizing SCM is the task of maintaining the configurations of evolving software systems. In this paper, we provide an approach to resolving some of the conceptual and technical problems in maintaining configurations of evolving software systems.
K. Narayanaswamy, Walt Scacchi
openaire   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Assessing optimal software architecture maintainability [PDF]

open access: yesProceedings Fifth European Conference on Software Maintenance and Reengineering, 2002
Over the last decade, several authors have studied the maintainability of software architectures. In particular, the assessment of maintainability has received attention. However, even when one has a quantitative assessment of the maintainability of a software architecture, one still does not have any indication of the optimality of the software ...
Jan Bosch, PerOlof Bengtsson
openaire   +1 more source

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