Results 41 to 50 of about 1,870,230 (325)
Estimating Maintenance Cost for Web Applications [PDF]
Informatică economică, 2016 The current paper tackles the issue of determining a method for estimating maintenance costs for web applications. The current state of research in the field of web application maintenance is summarized and leading theories and results are highlighted ...
Ion IVAN, Mihai Liviu DESPA
doaj +1 more source
Bug Localization Model in Source Code Using Ontologies
IEEE Access, 2023 The bug location process aims to identify source code artifacts associated with reported bugs. Manual bug location is burdensome for programmers who must reproduce and analyze the bug to identify the defective artifact and perform necessary maintenance ...
Alisson Solitto da Silva +2 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Exploring Code Clones in Programmable Logic Controller Software
, 2017 The reuse of code fragments by copying and pasting is widely practiced in software development and results in code clones. Cloning is considered an anti-pattern as it negatively affects program correctness and increases maintenance efforts.
Egyed, Alexander +3 more
core +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Early Detection of Flawed Structural Dependencies During Software Evolution
IEEE Access, 2021 During software evolution, complex structural dependencies between source files pose a great challenge on maintenance activities. Some of these dependencies propagate defects among files, incurring frequent bugs or changes, and consuming significant ...
Di Cui
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Pattern Based Software Architecture for Predictive Maintenance [PDF]
, 2022 Ants Torim +3 more
openalex +1 more source
Rationale Management Challenges in Requirements Engineering [PDF]
, 2010 Rationale and rationale management have been playing an increasingly prominent role in software system development mainly due to the knowledge demand during system evaluation, maintenance, and evolution, especially for large and complex systems.
Avgeriou, Paris, +2 more
core +3 more sources