Results 91 to 100 of about 3,483,326 (328)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

A Risk Measurement Model of Software Project Based on Grey Variable Weight Clustering analysis

Chemical Engineering Transactions, 2016
Effectively identifying and analyzing risks are critical to ensuring the quality of software project. Risk measurement analysis of software project is a process of multi-factor, fuzziness, hierarchy and complexity, in response to which we carry out a ...
N. He, X. Mao
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

A high-sensitivity flexible bionic tentacle sensor for multidimensional force sensing and autonomous obstacle avoidance applications

Microsystems & Nanoengineering
Bionic tentacle sensors are important in various fields, including obstacle avoidance, human‒machine interfaces, and soft robotics. However, most traditional tentacle sensors are based on rigid substrates, resulting in difficulty in detecting ...
Xinyu Liu, Kunru Li, Shuo Qian, Lixin Niu, Wei Chen, Hui Wu, Xiaoguang Song, Jie Zhang, Xiaoxue Bi, Junbin Yu, Xiaojuan Hou, Jian He, Xiujian Chou   +12 more
doaj   +1 more source

A Graph Embedding Method Based on Sparse Representation for Wireless Sensor Network Localization

International Journal of Distributed Sensor Networks, 2014
In accordance with the problem that the traditional trilateral or multilateral estimation localization method is highly dependent on the proportion of beacon nodes and the measurement accuracy, an algorithm based on kernel sparse preserve projection ...
Xiaoyong Yan, Aiguo Song, Hao Yan
doaj   +1 more source

A Software-based Low-Jitter Servo Clock for Inexpensive Phasor Measurement Units

, 2018
This paper presents the design and the implementation of a servo-clock (SC) for low-cost Phasor Measurement Units (PMUs). The SC relies on a classic Proportional Integral (PI) controller, which has been properly tuned to minimize the synchronization ...
Brunelli, Davide, Fontanelli, Daniele, Laverty, David, Macii, David, Tosato, Pietro   +4 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The application of vibration tactile stimulation in hand motor imagery paradigm: a pilot study

Brain-Apparatus Communication
Background The motor imagery (MI) paradigm is widely used in active brain-computer interfaces (BCIs), but its effectiveness is hindered by accuracy limitations and individual variability.
Wenbin Zhang, Aiguo Song, Hexuan Hu, Minmin Miao, Baoguo Xu   +4 more
doaj   +1 more source

Software system safety [PDF]

Software itself is not hazardous, but since software and hardware share common interfaces there is an opportunity for software to create hazards. Further, these software systems are complex, and proven methods for the design, analysis, and measurement of
Uber, James G.
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source