Results 91 to 100 of about 891,695 (342)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Application of Blockchain Technologies in Verification of Software Metrics

open access: yesApplied Sciences
When creating software, it is important to focus not only on the functionality requested by users but also on ensuring that the software exhibits qualities such as maintainability, testability, comprehensibility, and reusability.
Jovan Milutinović   +4 more
doaj   +1 more source

AUTOMATING SOFTWARE DEVELOPMENT PRODUCTIVITY METRICS [PDF]

open access: yes, 1990
Measurement of software development productivity is needed in order to control software costs, but it is discouragingly labor-intensive and expensive. Computer aided software engineering (CASE) technologies -- especially object-oriented, integrated CASE -
Banker, Rajiv D.   +4 more
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Pragmatic quality metrics for evolutionary software development models [PDF]

open access: yes
Due to the large number of product, project, and people parameters which impact large custom software development efforts, measurement of software product quality is a complex undertaking.
Royce, Walker
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Software Measurement and Defect Prediction with Depress Extensible Framework

open access: yesFoundations of Computing and Decision Sciences, 2014
Context. Software data collection precedes analysis which, in turn, requires data science related skills. Software defect prediction is hardly used in industrial projects as a quality assurance and cost reduction mean. Objectives.
Madeyski Lech, Majchrzak Marek
doaj   +1 more source

Static Analyser for Java-Based Object-Oriented Software Metrics [PDF]

open access: yes, 1999
Software metrics play a major role In the software development. Not only software metrics help in understanding the size and complexity of software systems, but they are also helpful in improving the quality of software systems.
Abu Al-Ese, Hasan Mugbil Khalaf
core  

How Scale Affects Structure in Java Programs

open access: yes, 2015
Many internal software metrics and external quality attributes of Java programs correlate strongly with program size. This knowledge has been used pervasively in quantitative studies of software through practices such as normalization on size metrics ...
Lopes, Cristina V., Ossher, Joel
core   +1 more source

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