Results 91 to 100 of about 4,534,833 (370)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Application of Blockchain Technologies in Verification of Software Metrics
Applied SciencesWhen creating software, it is important to focus not only on the functionality requested by users but also on ensuring that the software exhibits qualities such as maintainability, testability, comprehensibility, and reusability.
Jovan Milutinović +4 more
doaj +1 more source
Entropy Churn Metrics for Fault Prediction in Software Systems
Entropy, 2018 Fault prediction is an important research area that aids software development and the maintenance process. It is a field that has been continuously improving its approaches in order to reduce the fault resolution time and effort.
Arvinder Kaur, Deepti Chopra
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Assessing Evolution of Microservices Using Static Analysis
Applied SciencesMicroservices have gained widespread adoption in enterprise software systems because they encapsulate the expertise of specific organizational subunits. This approach offers valuable insights into internal processes and communication channels.
Amr S. Abdelfattah +5 more
doaj +1 more source
Estimation of Defect proneness Using Design complexity Measurements in Object- Oriented Software
, 2009 Software engineering is continuously facing the challenges of growing complexity of software packages and increased level of data on defects and drawbacks from software production process.
Nair, T. R. Gopalakrishnan +2 more
core +1 more source
Using Metrics for Risk Prediction in Object-Oriented Software: A Cross-Version Validation
, 2021 Salim Moudache, Mourad Badri
openalex +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
The Making of Cloud Applications An Empirical Study on Software Development for the Cloud
, 2015 Cloud computing is gaining more and more traction as a deployment and provisioning model for software. While a large body of research already covers how to optimally operate a cloud system, we still lack insights into how professional software engineers ...
Barker A. +6 more
core +1 more source