Results 101 to 110 of about 6,716,277 (303)
Maleku: an evolutionary visual software analytics tool for providing insights into software evolution [PDF]
, 2011 Software maintenance is a complex process that requires the understanding and comprehension of software project details. It involves the understanding of the evolution of the software project, hundreds of software components and the relationships among ...
García-Peñalvo, Francisco +4 more
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A Process For Performance Evaluation Of Real-Time Systems [PDF]
Journal of Systemics, Cybernetics and Informatics, 2003 Real-time developers and engineers must not only meet the system functional requirements, but also the stringent timing requirements. One of the critical decisions leading to meeting these timing requirements is the selection of an operating system under
Andrew J. Kornecki, Eric Sorton
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Mapping Process Capability Models to Support Integrated Software Process Assessments
CLEI Electronic Journal, 2018 Software process assessments have been used to verify the conformance with quality reference models or standards, usually in a context of software process improvement programs.
Marcello Thiry +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Organizational Change Perspectives on Software Process Improvement [PDF]
Many software organizations have engaged in Software Process Improvement (SPI) and experienced the challenges related to managing such complex organizational change efforts.
Balshøj, Hans Henrik +2 more
core
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
The Synonym management process in SAREL [PDF]
, 2002 The specification phase is one of the most important and least supported parts of the software development process. The SAREL system has been conceived as a knowledge-based tool to improve the specification phase.
Castell Ariño, Núria +1 more
core +1 more source