Results 101 to 110 of about 2,610,840 (298)

Control of cognitive processes during software design: what tools are needed? [PDF]

, 1988
Raymonde Guindon, Bruce Curtis
openalex   +1 more source

The instrument control unit processing hardware and software of the wide field monitor on eXTP [PDF]

, 2022
Emrah Kalemci, Onur Turhan, I. Kuvvetli, Stéphane Schanne, M. Hernanz, P. Orleański, C. Tenzer, Müberra Sungur, Ahmet Onat, Ayhan Bozkurt, Mehmet A. Baltaci, J. L. Gálvez Sanchez, S. Brandt, Konrad Skup, Denis Tcherniak, Małgorzata Michalska   +15 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Improving processor reliability using software protection techniques.

, 2020
Y. Nezzari
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Antipatterns: A Compendium of Bad Practices in Software Development Processes [PDF]

International Journal of Interactive Multimedia and Artificial Intelligence, 2011
This Article presents a set of software process antipatterns, which arise as a result of bad practices within application development processes. Process AntiPatterns warn us about the harmful effects that may arise in projects, and also describe the ...
Victor Hugo Medina Garcia, Rubén Gonzalez Crespo, Sandro Javier Bolaños Castro   +2 more
doaj  

Image-Processing Software [PDF]

, 2004
It goes without saying that every CCD camera needs good software to control the camera and to process the final image. However, more often than not, amateurs struggle to get the software to do what they want and, for most people, there just aren’t enough spare hours in their busy working lives to wade through that enormous “user’s manual’.
openaire   +1 more source

Graphical Visualization of Risk Assessment for Effective Risk Management during Software Development Process [PDF]

, 2012
Raghavi K Bhujang, V. Suma
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source