Results 101 to 110 of about 15,785,349 (300)

Lessons Learned from Co-Evolution of Software Process and Model-Driven Engineering

open access: yes, 2016
Software companies need to cope with permanent changes in market. To stay competitive it is often inevitable to improve processes and adopt to new technologies.
Schmied, Andreas I.   +8 more
core   +1 more source

ProcessM: Intelligent Process Mining software

open access: yesSoftwareX
Contemporary software guides and executes various business processes, such as production, delivery of goods, sales, and official procedures. However, due to software flexibility, unforeseen circumstances, and exceptional conditions, processes may not ...
Tomasz P. Pawlak, Jędrzej Potoniec
doaj   +1 more source

Aplicação e análise de processo de desenvolvimento de software: um estudo de caso no GPES-IFPB

open access: yesRevista Principia, 2018
The Software Engineering Research Group from the Federal Institute of Paraiba is developing a research to identify and publicize on the web the best practices in software development processes, seeking to propagate their use among professionals and ...
Samyra Lara Ferreira Almeida   +5 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Software Package STATISTICA and Educational Process

open access: yesSHS Web of Conferences, 2016
The paper describes the main aspects of application of the software package STATISTICA in the educational process. Technologies of data mining which can be useful for students researches have been considered.
Demidova Liliya   +7 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

A Process For Performance Evaluation Of Real-Time Systems [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2003
Real-time developers and engineers must not only meet the system functional requirements, but also the stringent timing requirements. One of the critical decisions leading to meeting these timing requirements is the selection of an operating system under
Andrew J. Kornecki, Eric Sorton
doaj  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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