Results 121 to 130 of about 6,716,277 (303)
Factors Models of Scrum Adoption in the Software Development Process: A Systematic Literature Review [PDF]
ReCIBE, 2018 (Background) The adoption of Agile Software Development (ASD), in particular Scrum, has grown significantly since its introduction in 2001. However, in Lima, many ASDs implementations have been not suitable (uncompleted or inconsistent), thus losing ...
Marilyn Sihuay +2 more
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Software handlers for process interfaces [PDF]
Process interfaces are developed in an effort to reduce the time, effort, and money required to install computer systems. Probably the chief obstacle to the achievement of these goals lies in the problem of developing software handlers having the same ...
Bercaw, R. W.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Image-Processing Software [PDF]
, 2004 It goes without saying that every CCD camera needs good software to control the camera and to process the final image. However, more often than not, amateurs struggle to get the software to do what they want and, for most people, there just aren’t enough spare hours in their busy working lives to wade through that enormous “user’s manual’.
openaire +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
PROCESS SIMULATION IN SUPPLY CHAIN USING LOGWARE SOFTWARE [PDF]
The authors present basis of simulation usage in managerial decisionsupport focusing on the supply chain processes. In the beginning the need for simulationis presented, then advantages and disadvantages of simulation experiments and thesimulation tools ...
Beata Åšlusarczyk, Sebastian Kot
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source