Results 161 to 170 of about 15,785,349 (300)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Transition management of software process improvement

, 2017
Process improvement studies have tended to focus on software process improvement (SPI) framework such as the generic,best practices" models (e.g., CMM and SPICE), SPI Models (e.g., PDCA and IDEAL), and Quality Improvement Paradigm (QIP ...
최병주
core  

The Multi-Author Practical Scoping (MAPS) Model: Practical Guidance for Collaborative Scoping Reviews in Health Professions Education. [PDF]

Clin Teach
Stelling H, Brown M, Boyle A, Higgins C, Burford B, Vance G.   +5 more
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Data capture, collection, management, and storage systems for clinical research: A scoping review protocol. [PDF]

PLoS One
Molano-González N, Moreno-Chaparro J.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Software process improvement

, 2014
SOFTWARE PROCESS
core  

Utilizing strategy mapping software for participatory evaluation of crisis management efforts: A case study. [PDF]

PLoS One
Björnqvist A, Jonson CO, Prytz E, Johansson BJE, Berggren P.   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A systematic mapping study method for software architecture research with LLM-assisted quality assessment. [PDF]

MethodsX
Olar A, Picus O, Cernău L, Dioșan L, Motogna S.   +4 more
europepmc   +1 more source