Results 131 to 140 of about 2,162,371 (314)

Research in software allocation for advanced manned mission communications and tracking systems [PDF]

open access: yes
An assessment of the planned processing hardware and software/firmware for the Communications and Tracking System of the Space Station Freedom (SSF) was performed.
Kusmanoff, Antone   +2 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Análisis de experiencias de mejora de procesos de desarrollo de software en PYMEs

open access: yesCiencia UNEMI, 2017
The services of the software development companies are based on producing high quality software products. Software products quality is ensured by applying software engineering practices throughout the development process.
Coque-Villegas, Shirley   +3 more
doaj  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Analysis of Production Process Performance Using Computer

open access: yesManagement Systems in Production Engineering
Planning a production process in terms of correctly defining its efficiency, duration and the level of generated costs is a difficult task. Manufacturing processes are characterized by a high level of complexity and are exposed to a large number of ...
Pawlak Szymon, Fornalczyk Agnieszka
doaj   +1 more source

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