Results 111 to 120 of about 2,196,372 (288)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Ain Shams Engineering JournalThe growing complexity and demands for high-quality software underlined the need for robust automated software testing frameworks. However, lack of skilled personnel, cost of testing automation, and maintenance of script along with others oppose the ...
Muhammad Faisal Abrar +6 more
doaj +1 more source
Impact of a process improvement program in a production software environment: Are we any better? [PDF]
For the past 15 years, Computer Sciences Corporation (CSC) has participated in a process improvement program as a member of the Software Engineering Laboratory (SEL), which is sponsored by GSFC.
Heller, Gerard H., Page, Gerald T.
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Software Development Processes [PDF]
Computer Science Journal of Moldova, 2004 For many years now, software process improvement (SPI) has been recognized as an effective way for companies to improve the quality of the software they produce and to increase the efficiency of the development process. Much work has gone into developing
V. Iacoban
doaj
Achieving higher capability maturity in construction process improvement [PDF]
Process improvement has been identified as one of the potential mechanisms to achieve the desired performance improvements within the UK construction industry.
Amaratunga, Dilanthi +2 more
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Ingeniería e Investigación, 2008 Organisations have been forced to change their philosophy due to the vast amount of information made available when running software process improvement (SPI) programmes and working in a way leading to maintaining and converting this information into ...
Joanna Capote +4 more
doaj