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Current Challenges and Proposed Software Improvement Process for VSEs in Developing Countries

open access: yes, 2016
Many software development organizations are classified as Very Small Entities (VSEs) with limited number of staff to implement full size of software development lifecycles standards (SDLC) such as ISO/IEC 12207 in their software projects.
Wen, Larry   +6 more
core   +1 more source

Understanding the perception of very small software companies towards the adoption of process standards [PDF]

open access: yes, 2010
This paper is concerned with understanding the issues that affect the adoption of software process standards by Very Small Entities (VSEs), there needs from process standards and there willingness to engage with the new ISO/IEC 29110 standard in ...
O'Connor, Rory   +9 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Speech Recognition Software—An Improvement to the Transcription Process?

open access: yesForum: Qualitative Social Research, 2008
The study outlined in this paper addresses the question: Does the use of speech recognition software allow a faster transcription of interview and audio recordings than traditional modes of transcription?
Thorsten Dresing   +2 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Organisational Readiness and Software Process Improvement [PDF]

open access: yes, 2007
The Capability Maturity Model Integration (CMMI) is a structured representation of software development processes that can support an organisation's software process improvement (SPI) strategies. However, CMMI and SPI initiatives generally exhibit low levels of adoption and limited success.
Mahmood Niazi   +2 more
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Combining Capability Assessment and Value Engineering: a New Two-dimensional Method for Software Process Improvement [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2008
During the last decades software process improvement (SPI) has been recognized as a usable possibility to increase the quality of software development. Implemented SPI investments have often indicated increased process capabilities as well. Recently more
Pasi Ojala
doaj  

Methodology for Process Improvement Through Basic Components and Focusing on the Resistance to Change.

open access: yes, 2010
This paper describes a multi-model methodology that implements a smooth and continuous process improvement, depending on the organization's business goals and allowing users to establish their improvement implementation pace.
Calvo-Manzano Villalon, Jose Antonio   +11 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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