Results 81 to 90 of about 713,154 (305)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Software process improvement: Awareness, use, and benefits in Canadian software development firms

RAE: Revista de Administração de Empresas, 2017
Since 1982, the software development community has been concerned with the delivery of quality systems. Software process improvement (SPI) is an initiative to avoid the delivery of low quality systems.
Delroy Chevers
doaj  

Tuning COCOMO-II for Software Process Improvement: A Tool Based Approach [PDF]

Mehran University Research Journal of Engineering and Technology, 2016
In order to compete in the international software development market the software organizations have to adopt internationally accepted software practices i.e.
SYEDA UMEMA HANI, ABU TURAB ALAM, ABDUL BASIT SHAIKH   +2 more
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Evidence-Based Quality-Aware Agile Software Development Process: Design and Evaluation

IEEE Access
Agile software development (ASD) aims to deliver high-quality software. However, software quality often receives less attention in ASD due to focus on functionality.
Pertti Karhapaa, Woubshet Behutiye, Pertti Seppanen, Pilar Rodriguez, Markku Oivo, Xavier Franch, Silverio Martinez-Fernandez, Lidia Lopez, Michal Choras, Alessandra Bagnato, Sanja Aaramaa, Jari Partanen   +11 more
doaj   +1 more source

An evaluation of software development practice and assessment-based process improvement in small software development firms [PDF]

, 2004
[Abstract]: As software becomes increasingly important to all aspects of industry, there is a need to encourage practitioners to adopt best practice so as to improve the quality of the processes in use, and therefore achieve targets relating to time ...
Cater-Steel, Aileen
core  

Gamification as strategy for software process improvement: A systematic mapping [Gamificación como estrategia para la Mejora de procesos software: Un mapeo Sistemático]

, 2017
Actually, software development companies face major challenges related to the implementation of high quality software products at even-increasing speed.
Hincapie J.A., Gloria Piedad Gasca-Hurtado, Jesus Andres Hincapie, Gasca-Hurtado G.P., Gomez-Alvarez M.C., Maria Clara Gomez-Alvarez   +5 more
core   +1 more source

Software Process Dynamics: Modeling, Simulation and Improvement [PDF]

, 2006
The aim of this chapter is to introduce the reader to the dynamics of the software process, the ways to represent and formalize it, and how it can be integrated with other techniques to facilitate, among other things, process improvement.
Toro Bonilla, Miguel, Acuña, Silvia T. (Coordinador), Sánchez Segura, María I. (Coordinador), Ramos Román, Isabel, Ruiz Carreira, Mercedes   +4 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Software process improvement: assessments for small software firms

, 2010
As software becomes increasingly important to all aspects of industry, there is a need to encourage practitioners to adopt best practice so as to improve the quality of the processes in use, and therefore achieve targets relating to time, budget and ...
Cater-Steel, Aileen
core