Results 81 to 90 of about 2,245,735 (312)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Le contrôle de la forme des réseaux par leurs membres : le fil de discussion comme réseau d’interaction

open access: yesSociologies, 2015
This article investigates the coordination modes on electronic mailing lists showing that a thread can be identified as a replies network extending from the dynamics of the interaction process.
Alexandre Delanoë, Bernard Conein
doaj  

A New Optimized Hybrid Model Based On COCOMO to Increase the Accuracy of Software Cost Estimation [PDF]

open access: yesJournal of Advances in Computer Engineering and Technology, 2018
The literature review shows software development projects often neither meet time deadlines, nor run within the allocated budgets. One common reason can be the inaccurate cost estimation process, although several approaches have been proposed in this ...
Ramin Saljoughinejad, Vahid Khatibi
doaj  

COMPARISON ON OPEN SOURCE COLLABORATIVE PROJECT MANAGEMENT SOFTWARE [PDF]

open access: yes
Modern concepts, like team collaboration and project management, have to backed up by modern software tools, with economic efficiency.Open Source, Collaborative, Project Management ...
Cosmin MARIN
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Large Language Models for Early-Stage Software Project Estimation: A Systematic Mapping Study

open access: yesApplied Sciences
Accurate estimation of software project characteristics during the early stages of development remains a constant challenge in software projects.
Łukasz Radliński, Jakub Swacha
doaj   +1 more source

Software Development Factories, the Project Management Perspective [PDF]

open access: yes
In a software factory, the applications are developed in the same way Henri Ford started manufacturing cars. In such a way, a customized solution could be obtained within a reasonable budget and within the foreseen timeframe.
Felician ALECU
core  

Summary of the First Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE1)

open access: yes, 2014
Challenges related to development, deployment, and maintenance of reusable software for science are becoming a growing concern. Many scientists’ research increasingly depends on the quality and availability of software upon which their works are built ...
Ketan Maheshwari   +35 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Exploring the role of commercial stakeholders in open source software evolution

open access: yes, 2012
Copyright @ 2012 SpringerIt has been lately established that a major success or failure factor of an OSS project is whether it involves a commercial company, or more extremely, when the project management is in the hands of a commercial software ...
Andrea Capiluppi   +17 more
core   +1 more source

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