Results 111 to 120 of about 428,429 (314)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Neural networks for predicting the duration of new software projects
, 2015 The duration of software development projects has become a competitive issue: only 39% of them are finished on time relative to the duration planned originally.
Abran, A., Lopez-Martin, C.
core +1 more source
PERFORMANCE EVALUATION OF PROJECTS IN SOFTWARE DEVELOPMENT
Havacılık ve Uzay Teknolojileri Dergisi, 2015 IT firms are able to develop various types of software development projects from small sized projects to very large ones. A software development process is carried out by different stages of the project management such as analysis, design, development ...
Filiz Çetin, Çiğdem Alabaş-Uslu
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Data Integration by Software Tools From Software Projects
, 2016 Bu tezde değişik yazılım projelerinden veri toplama ve birleştirme amaçlanmıştır. Değişik yazılım projelerinden veri toplama ve birleştirmede zorluklar vardır. Bazı tekniklerin bazı proje takımlarına ve durumlarına daha iyi uyduğu saptanmıştır.
Adrah, Muna, Mıshra, Alok
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Estimation metrics in software projects
, 2018 A software product that implements a hybrid metric was developed. It articulates relevant characteristics of three estimation metrics in Communication and Information Technology (CIT) development projects: (i) history points, (ii) use case points, (iii ...
ROJAS PUENTES, MARIA DEL PILAR +3 more
core +1 more source
SoftwareXThis paper presents Depex, a tool that allows developers to reason over the entire configuration space of the dependencies of an open-source software repository.
Antonio Germán Márquez +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Competence Development in IT Projects through Education and Training Programmes [PDF]
The paper refers to the quality of training and education on IT project management. A survey was made and the main results are presented. 81 % of the responses came from China. The rest were professionals of different EU nationalities.
Constanta-Nicoleta BODEA, Melania COMAN
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