Results 51 to 60 of about 428,429 (314)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

A General Framework for Teaching Software Engineering and Improving Collaboration Skills in Multidisciplinary Teams

open access: yesHavacılık ve Uzay Teknolojileri Dergisi, 2021
International Engineering Accreditation (IEA) organization measure and improve the quality of the engineering education in universities. This paper presents a framework for Software Engineering Education in line with the IEA criteria. A multidisciplinary
Dionysis GOULARAS   +3 more
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

An Evaluation of Software Project Risk Management in South Africa

open access: yesSouth African Journal of Industrial Engineering, 2013
Global research indicates that the success rate of software projects worldwide is currently very low, and has been low for the past few decades. The application of risk management has improved the success rate of software projects in the developed world.
De Wet, B., Visser, J. K.
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

A software process engineering approach to improving software team productivity using socioeconomic mechanism design [PDF]

open access: yes, 2011
Software development involves teams of interconnected individuals who are encouraged to work collectively in a knowledge and communication network to produce software artifacts.
O'Connor, Rory   +7 more
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

ReBEC: A Method for Capturing Experience during Software Development Projects

open access: yes, 2010
In software organizations, usual ways to capture the experience project team members acquire are based on methods such as project postmortem analysis, post-project revisions and others alike. Their main drawback is that the experience capture is done (if
Andrés Silva   +3 more
core   +1 more source

Project risk management in Iranian software projects [PDF]

open access: yesJournal of Engineering Management and Competitiveness, 2018
Many Software development organizations suffer chronic problems of cost overruns, schedule slips and projects that do not meet the originally specified functions in almost all software projects.
Afshari Ali Reza   +2 more
doaj  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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