Results 91 to 100 of about 11,449,331 (358)
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
A refactoring categorization model for software quality improvement. [PDF]
Almogahed A+6 more
europepmc +1 more source
On the Relation of Test Smells to Software Code Quality
Test smells are sub-optimal design choices in the implementation of test code. As reported by recent studies, their presence might not only negatively affect the comprehension of test suites but can also lead to test cases being less effective in finding
D. Spadini+4 more
semanticscholar +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Assessing the impact of software quality models in healthcare software systems. [PDF]
Ronchieri E, Canaparo M.
europepmc +1 more source
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti+10 more
wiley +1 more source
Software Code Smell Prediction Model Using Shannon, Rényi and Tsallis Entropies
The current era demands high quality software in a limited time period to achieve new goals and heights. To meet user requirements, the source codes undergo frequent modifications which can generate the bad smells in software that deteriorate the quality
Aakanshi Gupta+5 more
doaj +1 more source
Improving bioinformatics software quality through incorporation of software engineering practices. [PDF]
Noor A.
europepmc +1 more source