Results 71 to 80 of about 11,455,886 (297)

Strategic drivers of software quality: beyond external and internal software quality [PDF]

Proceedings Second Asia-Pacific Conference on Quality Software, 2002
Software quality is often considered in terms of the contractual requirements between the supplier and acquirer as described in ISO/IEC 12207 and focuses on software life cycle processes. However, beyond these processes acquirer organisations need to address other issues like complying with new legislation, securing return on investment, and achieving ...
openaire   +5 more sources

Open Source, Agile and Reliability Measures [PDF]

, 2009
As open source and agile development do work in some circumstances, particularly with regard to shorter and more frequent release policy, we wonder whether the defect profile (reliability growth) found in the open-source projects so far is typical of ...
McBride, TM, Syed Mohamad, SM
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Considerations for regulation and evaluation of digital mental health technologies

Digital Health
Digital mental health technologies (DMHTs) are becoming well established within mental health services and through direct-to-consumer models. Due to their scalable nature, DMHTs may support services to bridge the gap between demand and the available ...
Gareth Hopkin, Richard Branson, Paul Campbell, Holly Coole, Sophie Cooper, Francesca Edelmann, Mark Salmon   +6 more
doaj   +1 more source

Q-Rapids: Quality-Aware Rapid Software Development: an H2020 Project [PDF]

, 2019
This work reports the objectives, current state, and outcomes of the Q-Rapids H2020 project. Q-Rapids (Quality-Aware Rapid Software Development) proposes a data-driven approach to the production of software following very short development cycles.
Oriol Hilari, Marc, López Cuesta, Lidia
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Towards optimising non-functional requirements

, 2009
Non-functional requirements are an important, and often critical, aspect of any software system. However, determining the degree to which any particular software system meets such requirements and incorporating such considerations into the software ...
Christopher Burgess, Jiang, L., Burgess, C., Aneesh Krishna, Krishna, A., Li Jiang   +5 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Quality-aware Rapid Software Development Project: The Q-Rapids Project [PDF]

, 2019
Software quality poses continuously new challenges in software development, including aspects related to both software development and system usage, which significantly impact the success of software systems.
Oriol Hilari, Marc, Franch Gutiérrez, Javier, López Cuesta, Lidia, Trendowicz, Adam, Rodríguez, Pilar, Martinez Fernandez, Silverio   +5 more
core   +1 more source