Results 81 to 90 of about 6,609 (259)

Investigating the influence of urban green spaces on urban heat island mitigation – taking four districts in Shijiazhuang as an example

Journal of Environmental Engineering and Landscape Management
The primary objective of this scholarly investigation is to elucidate the intricate interplay between the urban heat island (UHI) effect and municipal green spaces.
Nan Zhang, Qiuning Ding, Haitao Wang
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Patient's self-evaluation of two education programs for age-related skin changes in the face: a prospective, randomized, controlled study

Clinical, Cosmetic and Investigational Dermatology, 2011
Linda M Williams1, Jane E Alderman2, Garry Cussell3, John Goldston4, Neal Hamilton5, Adrian C Lim6, Greg J Goodman7, Michael B Halstead8, John D Rogers81Artisan Rejuvenation Clinic, Fortitude Valley, Queensland; 2The Clinic for Essential Beauty, Adelaide,
Williams LM, Alderman JE, Cussell G, Goldston J, Hamilton N, Lim AC, Goodman GJ, Halstead MB, Rogers JD   +8 more
doaj  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The Effect of Extract of Internal Layer of Quercus(Oak)Fruit in Contraction of Vaginal Muscles in Women with Vaginal Relaxation

Journal of Medicinal Plants, 2016
Background: The Quercus (oak) fruit and especially the internal layer of the fruit (jaft) is rich in tannin and due to its astringent effects on the smooth muscles.
N Lorzadeh, F Sepavand, M Solimaninezhad, N Kazemirad   +3 more
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Influence of birch bark dusting intensity on the peculiarities of the course of pollinosis in children

Аллергология и Иммунология в Педиатрии
Rationale: the problem of the growth of allergic diseases associated with plant pollination is urgent. At present, numerous works discuss the influence of global warming on the onset, intensity and duration of plant pollination.
E. V. Stezhkina, N. A. Belykh, K. I. Ulyanov, E. S. Busareva, A. I. Agapova, J. М. Seleznyova, V. S. Karasyova   +6 more
doaj   +1 more source