Results 81 to 90 of about 738 (240)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Achieving Representative Faultloads in Software Fault Injection
, 2011 Given the complexity of modern software systems and its pervasiveness in many aspects of our lives, software faults (i.e., bugs) are a dangerous threat.
Natella, Roberto
core
Modeling and analysis of software rejuvenation in a server virtualized system
, 2010 As server virtualization is used as an essential software infrastructure of various software services such as cloud computing, availability management of server virtualized system is becoming more significant. Although time-based software rejuvenation is
Machida, Fumio +5 more
core +1 more source
Assessment of Aging and Rejuvenation for Resiliency in Heterogeneous Network Clusters
, 2023 The problem of evaluating the application of software rejuvenation is challenging, especially when load balancing comes into play to overcome resiliency threats.
Camilli, Matteo +6 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Analysis of software cost models with rejuvenation
, 2000 Software rejuvenation is a preventive maintenance technique that has been extensively studied in the recent literature. In this paper, we extend the classical result by Huang, Kintala, Kolettis and Fulton (1995), and in addition propose a modified ...
Tadashi Dohi
core
STUDY OF EYE HEALTH RISKS ASSOCIATED WITH DECORATIVE COSMETICS AND AESTHETIC PROCEDURES
Trakia Journal of SciencesINTRODUCTION: The cosmetic industry has seen significant growth, with an increasing number of men utilizing procedures and rejuvenation therapies. This shift has expanded the consumption of cosmetic services but also raised concerns about risks affecting
T. Mihova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Optimum Software Aging Prediction and Rejuvenation Model for Virtualized Environment
, 2016 Advancement in electronics and hardware has resulted in multiple softwares running on the same hardware. The result is multiuser, multitasking and virtualized environments.
Srinivasan, G N, Umesh, I M
core +1 more source