Results 91 to 100 of about 3,019,176 (294)

Modeling and Analysis of Software Aging and Rejuvenation

, 2000
Software systems are known to suffer from outages due to transient errors. Recently, the phenomenon of “software aging”, one in which the state of the software system degrades with time, has been reported.
Kalyanaraman Vaidyanathan, Kishor S. Trivedi   +1 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Spatial Feature and Its Formation Mechanism of the Population and Land Urbanization Coordination Degree in the Yangtze River Economic Belt

Shuitu baochi yanjiu, 2021
The coordination of population urbanization and land urbanization has a strategic influence on the Yangtze River Economic Belt. The coordination degree of the Yangtze River Economic Belt from 2000 to 2018 was calculated and analyzed in the terms of ...
CHEN Xicai, PENG Yanmei, WANG Xueliang, XU Yongtao, WANG Tianqiang, PAN Yujun   +5 more
doaj  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

STUDY OF EYE HEALTH RISKS ASSOCIATED WITH DECORATIVE COSMETICS AND AESTHETIC PROCEDURES

Trakia Journal of Sciences
INTRODUCTION: The cosmetic industry has seen significant growth, with an increasing number of men utilizing procedures and rejuvenation therapies. This shift has expanded the consumption of cosmetic services but also raised concerns about risks affecting
T. Mihova, E. Georgieva, S. Trifonova-Laskova   +2 more
doaj   +1 more source

Compositional Fluid Stochastic Petri Net model for operational software system performance [PDF]

, 2008
Software systems experience gradual performance degradation due to several reasons and different preventive and corrective techniques can be applied to restore their performance level.
A. Bobbio, M. Telek, M. Gribaudo, GRIBAUDO, MARCO, A. Horvath, S. Garg, M. Sereno   +6 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Rejuvenation and Networking Motivates Librarians to Attend Conferences. A Review of: Vega, Robert D. and Ruth S. Connell. “Librarians’ Attitudes Toward Conferences: A Study.” College & Research Libraries 68.6 (2007): 503‐15.

Evidence Based Library and Information Practice, 2009
Objectives – To determine why professional librarians attend or do not attend conferences and to consider their attitudes toward the various conference offerings and whether conference attendance is important to their careers.Design – An electronic mail ...
Yvonne Hultman Özek
doaj  

Facially Driven Dynamic Navigation Guided Implant Surgery For Terminal Dentition

International Dental Journal
Introduction: Facial scan and 3D smile design play a crucial role in guiding implant-supported full-arch rehabilitation, ensuring optimal facial esthetics and functional outcomes. This approach facilitates face rejuvenation by restoring facial asthetics,
Hanqi Gao
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source