Results 31 to 40 of about 498,159 (256)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
International Journal of Computer Applications, 2016 of complex system is increased more rapidly. Size and complexity of computer systems has grown during last past few years in very impressive manner. Different Software reliability models have discovered since last 30 years. There has lot of work is done in field of software reliability estimation.
Durga Patel, Pallavi P
openaire +2 more sources
Assessment of expected reliability of applied software for computer-based information systems
Informatika, 2021 The reliability of computer-based information systems is largely determined by the reliability of the developed application software. The failure rate of its computer program is considered as an indicator of the reliability of the application software ...
S. M. Borovikov +4 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Applied SciencesThe importance of software has increased significantly over time, and software failures have become a critical concern. As software systems have diversified in functionality, their structure has become more complex, and the types of failures that can ...
Youn Su Kim +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Non-Parametric Approach for Survival Analysis of Component-Based Software [PDF]
International Journal of Mathematical, Engineering and Management Sciences, 2020 Reliability of a software or system is the probability of system to perform its functions adequately for the stated time period under specific environment conditions.
Sandeep Chopra +4 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Software Reliability Prediction Based on Recurrent Neural Network and Ensemble Method
ComputersSoftware reliability is a crucial factor in determining software quality quantitatively. It is also used to estimate the software testing duration. In software reliability testing, traditional parametric software reliability growth models (SRGMs) are ...
Wafa Alshehri +2 more
doaj +1 more source