Results 51 to 60 of about 17,556,152 (238)

Reliability Assessment Model of IMA Partition Software Using Stochastic Petri Nets

IEEE Access, 2021
In order to reduce the failure rate of Integrated Modular Avionics (IMA) partition software, due to the reliability block diagram (RBD) method, fault tree analysis (FTA) method and GO method cannot describe the state transition process of partition ...
Wu Zhijun, Ma Haolin, Yue Meng
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

An improved software reliability prediction model by using high precision error iterative analysis method

, 2019
Software reliability deals with the probability that software will not cause the failure of a system in a specified time interval. Software reliability growth models (SRGMs) are used to predict future behaviour from known characteristics of software ...
Jabeen, G.,, Gul Jabeen, Afzal, Wasif,, Ping Luo, Wasif Afzal, Luo, P.,   +5 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Developing a conceptual model for improving the software system reliability [PDF]

Problems of Information Society
In the Industry 4.0 environment, the software systems development methodology is rapidly evolving, flexible technologies and new programming languages are being applied.
Tamilla Bayramova, Nazakat Malikova
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

A Software Reliability Model Considering a Scale Parameter of the Uncertainty and a New Criterion

Mathematics
It is becoming increasingly common for software to operate in various environments. However, even if the software performs well in the test phase, uncertain operating environments may cause new software failures. Traditional proposed software reliability
Kwang Yoon Song, Youn Su Kim, Hoang Pham, In Hong Chang   +3 more
doaj   +1 more source

An executable software architecture model for response time and reliability assessment [PDF]

Management Science Letters, 2014
With the increasing use of the Unified Modeling Language (UML) diagrams to describe the software’s architecture and the importance of evaluating nonfunctional requirements at the level of software architecture, creating an executable model from these ...
Zahra Norouzi, Ali Harounabadi
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source