Results 41 to 50 of about 17,556,152 (238)
A model driven approach for software systems reliability [PDF]
, 2004 The reliability assurance of software systems from design to deployment level through transformation techniques and model driven approach, is described.
Rodrigues, GN, Emmerich, W, Rosenblum, D
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Assessment of expected reliability of applied software for computer-based information systems
Informatika, 2021 The reliability of computer-based information systems is largely determined by the reliability of the developed application software. The failure rate of its computer program is considered as an indicator of the reliability of the application software ...
S. M. Borovikov +4 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Software Reliability Prediction Based on Recurrent Neural Network and Ensemble Method
ComputersSoftware reliability is a crucial factor in determining software quality quantitatively. It is also used to estimate the software testing duration. In software reliability testing, traditional parametric software reliability growth models (SRGMs) are ...
Wafa Alshehri +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Confidence intervals for reliability growth models with small sample sizes [PDF]
, 2003 Fully Bayesian approaches to analysis can be overly ambitious where there exist realistic limitations on the ability of experts to provide prior distributions for all relevant parameters.
Quigley, J.L., Walls, L.A.
core +4 more sources
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Research on Software Reliability Model Prediction and Evaluation System
MATEC Web of Conferences, 2018 This paper analyzes the requirements of software reliability model prediction and evaluation system, describes the overall structure of the system, the specific module functions and the design of database.
Wang Ru
doaj +1 more source