Results 91 to 100 of about 6,176,166 (267)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Software system safety [PDF]

open access: yes
Software itself is not hazardous, but since software and hardware share common interfaces there is an opportunity for software to create hazards. Further, these software systems are complex, and proven methods for the design, analysis, and measurement of
Uber, James G.
core   +1 more source

Developing Educational Software: a professional tool perspective [PDF]

open access: yes, 2000
The selection, and use of educational software and its impact in schools are still controversial issues. In this paper we present an alternative conceptualisation of educational software based on considering the software as an instrument for teachers ...
Hinostroza, Juan Enrique   +3 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

A DISCUSSION ON ASSURING SOFTWARE QUALITY IN SMALL AND MEDIUM SOFTWARE ENTERPRISES: AN EMPIRICAL INVESTIGATION [PDF]

open access: yes, 2011
Under the studies of general core activities including software inspection, review and testing to achieve quality objectives in small-medium size enterprises (SMEs), the paper presents a contemporary view of such companies against quality measures.
Misra, Sanjay, Pusatli, O. T.
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

System for the Unified Management, Assessment, and Review of Information (SUMARI)

open access: yesJournal of the Medical Library Association, 2019
System for the Unified Management, Assessment, and Review of Information (SUMARI) is a web-based systematic review program provided by the Joanna Briggs Institute.
Christi Piper
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Symbolical Analysis of RF-Network Problems using Mason’s Rule [PDF]

open access: yes, 2012
We briefly review Mason’s rule for the computation of RF-network problems and show its implementation into the software package freeMASON. This tool solves symbolically Mason’s rule for any wave quantity and allows to derive analytical expressions as ...
Schwerg, N.
core   +1 more source

All-cause mortality risk following diabetic avoidable hospitalization among older patients with type 2 diabetes mellitus: a nationwide retrospective cohort study in South Korea

open access: yesBMC Public Health
Background In South Korea, the prognosis of avoidable hospitalization in diabetes has not been evaluated, even though the incidence rate is considerably high compared to the Organization for Economic Co-operation and Development average.
Woo-Ri Lee   +4 more
doaj   +1 more source

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