Results 51 to 60 of about 79,297 (257)
AbstractModern research is inescapably digital, with data and publications most often created, analyzed, and stored electronically, using tools and methods expressed in software. While some of this software is general‐purpose office software, a great deal of it is developed specifically for research, often by researchers themselves.
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
This study examines how corporate social responsibility (CSR) influences green purchase intentions in the banking services, aligning with the United Nations' Sustainable Development Goals (SDGs).
Hao Wu +2 more
doaj +1 more source
Introduction to the Software Sustainability Institute
Neil Chue Hong, Software Sustainability Institute Director, and Mario Antonioletti, Research Software Engineer, will give an overview of the important role that software plays in research and innovation and describe some of the Instituteʼs activities around the research software community in the UK and in Edinburgh. In particular, Neil & Mario will
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Conceptualizing a US Research Software Sustainability Institute (URSSI)
Poster for NSF S2I2 ...
Katz, Daniel S. +4 more
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Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The Work of the Software Sustainability Institute
A seminar given to the LIGM, Paris.
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Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
A talk presented as part of SIAM CSE 19 Conference within MS338 - Software Productivity and Sustainability for CSE and Data ...
Katz, Daniel S. +4 more
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