Results 41 to 50 of about 7,470,706 (245)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Premature Deaths and Socio-economic Status: The Role of Fine Particulate Matter in Türkiye (2019)

open access: yesThoracic Research and Practice
OBJECTIVE: Air pollution, particularly particulate matter (PM), is a leading environmental risk factor contributing to global morbidity and premature mortality.
Nilüfer Aykaç   +24 more
doaj   +1 more source

Deriving of Sequencing Strategies for Multi-Stage Productions Supported by Logistic Models and Software Tools

open access: yesProceedings of the Conference on Production Systems and Logistics, 2020
Sequencing as a core task of production control has a significant influence on the logistical performance and efficiency of a single work system. Particularly in the presence of sequence dependent setup times, systematic sequencing can increase the ...
Mütze, Alexander, Nyhuis, Peter
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Improving the Dynamic Performance of Five-Axis CNC Machine Tool by using the Software-in-the-Loop (SIL) Platform [PDF]

open access: yes, 2015
The paper presents the development and implementation of a Software-in-the-loop (SIL) platform allowing the real-time simulation of the hybrid model of five-axis CNC machine tool which is implemented in SIMULINK.
Pislaru, Crinela   +2 more
core   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Budget-aware random testing with T3: benchmarking at the SBST2016 testing tool contest [PDF]

open access: yes, 2016
Random testing has the advantage that it is usually fast. An interesting use case is to use it for bulk smoke testing, e.g. to smoke test a whole project. However, on a large project, even with random testing it may still take hours to complete.
Prasetya, S.W.B.   +2 more
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Software integration testing based on communication coverage criteria and partial model generation [PDF]

open access: yes, 2008
This paper considers the problem of integration testing the components of a timed distributed software system. We assume that communication between the components is specified using timed interface automata and use computational tree logic (CTL) to ...
Poore, J   +3 more
core   +5 more sources

A Comprehensive Approach for Monitoring Student Satisfaction in Blended Learning Courses

open access: yesCybernetics and Information Technologies, 2023
Due to the great importance of student satisfaction with educational services, many HEIs conduct annual surveys. Analyzing the results of such surveys, tracking trends, and comparing the evaluation results to help governing bodies make data-driven ...
Gaftandzhieva Silvia N.   +2 more
doaj   +1 more source

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