Results 51 to 60 of about 7,470,706 (245)

MSdeCIpher: A Tool to Link Data from Complementary Ionization Techniques in High-Resolution GC-MS to Identify Molecular Ions

open access: yesMetabolites, 2023
Electron ionization (EI) and molecular ion-generating techniques like chemical ionization (CI) are complementary ionization methods in gas chromatography (GC)-mass spectrometry (MS).
Daniel Stettin, Georg Pohnert
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Teaching Joint-Level Robot Programming with a New Robotics Software Tool

open access: yesRobotics, 2017
With the rising popularity of robotics in our modern world there is an increase in the number of engineering programs that offer the basic Introduction to Robotics course.
Fernando Gonzalez, Janusz Zalewski
doaj   +1 more source

Platform for Analysis and Labeling of Medical Time Series

open access: yesSensors, 2020
Reliable and diverse labeled reference data are essential for the development of high-quality processing algorithms for medical signals, such as electrocardiogram (ECG) and photoplethysmogram (PPG). Here, we present the Platform for Analysis and Labeling
Andrejs Fedjajevs   +3 more
doaj   +1 more source

Promoting and updating food frequency questionnaire tool to measure food consumption and nutrient intake analysis

open access: yesInternational Journal of Preventive Medicine, 2021
Background: One of the problems that nutritionists have always faced in research projects is the analysis of food intake of the subjects. Various approaches have been proposed in which the use of food frequency is one of the most used in this field. Many
Zahra Madani   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

PhosCancer: A comprehensive database for investigating protein phosphorylation in human cancer

open access: yesiScience
Summary: Protein phosphorylation is a crucial post-translational modification implicated in cancer pathogenesis, offering potential diagnostic and therapeutic targets.
Qun Dong   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

A Search-Based Approach to Multi-view Clustering of Software Systems [PDF]

open access: yes, 2015
—Unsupervised software clustering is the problem of automatically decomposing the software system into meaningful units. Some approaches solely rely on the structure of the system, such as the module dependency graph, to decompose the software systems ...
Hage, J.; id_orcid   +14 more
core   +2 more sources

Research and Development of a Costing Toolkit for Distance, Flexible and ICT-Based Education for Teacher Development in Africa

open access: yesOpen Praxis, 2007
Costing distance-education programmes is a key aspect of capacity building in many parts of the world. This paper reports on a research and development project to produce a new costing tool for Distance, Flexible and ICT-based Education (DFICTE) for ...
Frank R J Banks
doaj  

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