Results 71 to 80 of about 3,928,828 (299)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Virtual Simulation of Electric Bus Fleets for City Bus Transport Electrification Planning
Energies, 2020 City bus transport electrification has a strong potential of improving city air quality, reducing noise pollution and increasing passenger satisfaction.
Jakov Topić +4 more
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Prototyping Formal System Models with Active Objects
, 2018 We propose active object languages as a development tool for formal system models of distributed systems. Additionally to a formalization based on a term rewriting system, we use established Software Engineering concepts, including software product lines
Hähnle, Reiner, Kamburjan, Eduard
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
BuildingsConducting accurate and quick energy analyses for retrofitting purposes became crucial for Architecture, Engineering, Construction, and Operations (AECO) markets worldwide.
Rim Afa, Issam Sobhy, Abderrahim Brakez
doaj +1 more source
Development of the Personal Site of a Modern Scientist
Ukrainian Journal of Educational Studies and Information Technology, 2018 The article is devoted to the actual and practically important problem for modern science - to provide free access to the scientific creative heritage of the scientist.
Viacheslav Osadchyi +3 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Introduction to the Human Body With A Krama Inggil Language-Based Microcontroller ATmega 16 [PDF]
, 2012 The introduction of human limbs with language-based Krama Inggil ATmega microcontroller 16 is a tool that serves to introduce the members of the human body in one language Krama Inggil based microcontroller ATmega 16. This tool is made for the purpose
Desi, Ariyati
core