Results 71 to 80 of about 3,905,930 (301)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Virtual Simulation of Electric Bus Fleets for City Bus Transport Electrification Planning
Energies, 2020 City bus transport electrification has a strong potential of improving city air quality, reducing noise pollution and increasing passenger satisfaction.
Jakov Topić +4 more
doaj +1 more source
Open Source Tools to Support Teaching Agile Software Development [PDF]
, 2014 Learning agile software development methodologies are important due to the popularity of agility in software industry. Agile software development has several practices and each practice needs specific tools to work with.
Adhy, Satriyo, Wisnu Wirawan, Panji
core
Constraint specification by example in a Meta-CASE tool [PDF]
, 2009 CASE tools are very helpful to software engineers in different ways and in different phases of software development. However, they are not easy to specialise to meet the needs of particular application domains or particular software modelling ...
Qattous, H.K.
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Introduction to the Human Body With A Krama Inggil Language-Based Microcontroller ATmega 16 [PDF]
, 2012 The introduction of human limbs with language-based Krama Inggil ATmega microcontroller 16 is a tool that serves to introduce the members of the human body in one language Krama Inggil based microcontroller ATmega 16. This tool is made for the purpose
Desi, Ariyati
core
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
BuildingsConducting accurate and quick energy analyses for retrofitting purposes became crucial for Architecture, Engineering, Construction, and Operations (AECO) markets worldwide.
Rim Afa, Issam Sobhy, Abderrahim Brakez
doaj +1 more source
Development of the Personal Site of a Modern Scientist
Ukrainian Journal of Educational Studies and Information Technology, 2018 The article is devoted to the actual and practically important problem for modern science - to provide free access to the scientific creative heritage of the scientist.
Viacheslav Osadchyi +3 more
doaj +1 more source