Evaluating Software Tools for Lipid Identification from Ion Mobility Spectrometry-Mass Spectrometry Lipidomics Data. [PDF]
Molecules, 2023 Ross DH +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
NIST Mass Spectrometry Data Center standard reference libraries and software tools: Application to seized drug analysis. [PDF]
J Forensic Sci, 2023 Wallace WE, Moorthy AS.
europepmc +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Impact of Established and Emerging Software Tools on the Metabolite Identification Landscape. [PDF]
Front Toxicol, 2022 Smith AME +3 more
europepmc +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Better research software tools to elevate the rate of scientific discovery or why we need to invest in research software engineering. [PDF]
Front Bioinform, 2023 Deschamps J, Dalle Nogare D, Jug F.
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Recent advances and current landscape of software tools for image analysis and dosimetry in nuclear medicine. [PDF]
EJNMMI PhysBanda K +6 more
europepmc +1 more source
Integration of software tools for integrative modeling of biomolecular systems. [PDF]
J Struct Biol, 2022 Hancock M +6 more
europepmc +1 more source