Results 121 to 130 of about 1,095,552 (262)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Genotype imputation performance in Nellore cattle across different SNP panels and software tools. [PDF]

Trop Anim Health Prod
Campos G, Mulim HA, Ventura H, Souza N, Cardoso F, Oliveira HR.   +5 more
europepmc   +1 more source

Comparison of Three 3D Segmentation Software Tools for Hip Surgical Planning. [PDF]

Sensors (Basel), 2022
Mandolini M, Brunzini A, Facco G, Mazzoli A, Forcellese A, Gigante A.   +5 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Exploring free radiomics software tools: a multiparametric evaluation for cancer classification. [PDF]

BMC Med Imaging
Almeda-Luna E, Luna JM, Ventura S.
europepmc   +1 more source

Software tools and platforms in Digital Pathology: a review for clinicians and computer scientists. [PDF]

J Pathol Inform, 2022
Escobar Díaz Guerrero R, Carvalho L, Bocklitz T, Popp J, Oliveira JL.   +4 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Use as directed? A comparison of software tools intended to check rigor and transparency of published work. [PDF]

PLoS One
Eckmann P, Barnett A, Bannach-Brown A, Bascunan Atria EP, Cabanac G, Owen Franzen LD, Gazda MA, Hair K, Howison J, Kilicoglu H, Labbe C, McCann S, Nachev V, Roelandse M, Salholz-Hillel M, Schulz R, Ter Riet G, Vorland C, Bandrowski A, Weissgerber T.   +19 more
europepmc   +1 more source

Twitter integration of chemistry software tools. [PDF]

J Cheminform, 2021
Yoshikawa N, Kubo R, Yamamoto KZ.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source