Results 151 to 160 of about 2,614,876 (378)
Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content
Food Safety and Health, EarlyView.By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao +8 more
wiley +1 more source
Grassland Research, EarlyView.Plant species richness was greater in summer in both alpine and subalpine grassland ecosystems. Soil moisture demonstrates significant positive correlations with soil organic carbon and total nitrogen across seasonal periods. Microbial α‐diversity peaks during summer but maintains functional stability across seasons.
Huma Ali +4 more
wiley +1 more source
Metagenomic mining reveals novel Cas12 subtypes and their evolutionary diversification
iMetaOmics, EarlyView.We identified 4112 Cas12 Proteins and 6 new Cas12 subtypes, revealed their significant diversity in N‐terminal regions, repeat sequences, and sequences motifs. We developed an AI‐driven algorithm, Cas12fam, which allows precise annotation of 18 distinct domains in Cas12 proteins.
Meixia Yu +11 more
wiley +1 more source
Aquatic moss precipitates metals in the presence of a specific endophytic microbiome
iMetaOmics, EarlyView.Harnessing moss–microbe interactions for metal removal. Schematic representation of aquatic moss Warnstorfia fluitans and its microbial symbionts in the remediation of metal‐contaminated waters. Amplicon sequencing and advanced microscopy revealed microbial community composition and role of moss symbionts in metal accumulation within the moss tissues ...
Kaisa Lehosmaa +15 more
wiley +1 more source
Back to the future of soil metagenomics
Frontiers in Microbiology, 2016 Joseph eNesme +49 more
doaj +1 more source
Ribosomal RNA operon copy number: A trait‐informed framework to close the microbial cultivation gap
iMetaOmics, EarlyView.The vast majority of microbes remain uncultured, constraining functional validation and limiting microbiome‐based applications. We show that ribosomal RNA operon (rrn) copy number—a stable, phylogenetically conserved genomic trait—is strongly correlated with cultivation outcomes across ecosystems.
Yuxiao Huang +8 more
wiley +1 more source
Microbiological characterization of soil in Guadalupe Plateau, Piauí
, 2023 Francisco Cardozo Júnior +4 more
openalex +2 more sources
iMetaOmics, EarlyView.Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo +9 more
wiley +1 more source