Results 91 to 100 of about 43,636 (288)

Natural Allelic Variations in IbCHYR1–IbZnFR Complex Regulate Fusarium Root Rot Resistance in Sweet Potato

open access: yesAdvanced Science, EarlyView.
FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Huan Zhang   +14 more
wiley   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

open access: yesAdvanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song   +24 more
wiley   +1 more source

Transcriptome‐Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean

open access: yesAdvanced Science, EarlyView.
This study employs transcriptome‐wide association studies (TWAS) to identify 201 long non‐coding RNAs (lncRNAs) associated with seed weight. Expression quantitative trait locus (eQTL) analysis reveals dynamic and static regulatory variants controlling lncRNA expression across development.
Xiang Wang   +8 more
wiley   +1 more source

Resultados de pesquisa da Embrapa Soja - 2003: sementes e transferência de tecnologias. [PDF]

open access: yes, 2013
Tecnologia para a melhoria da qualidade de sementes de soja; Aperfeiçoamento e utilização de métodos para a melhoria da qualidade da semente de soja (04.2000.327-01); Estudo das técnicas de produção de sementes de soja (04.2000.327-03); Peletização de ...
SARAIVA, O. F.
core  

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang   +18 more
wiley   +1 more source

Desempenho e rendimento de carcaça de bezerros alimentados com colostro fermentado, associado ao óleo de soja e zeranol

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2004
Utilizaram-se 40 bezerros Holandês × Zebu distribuídos em oito tratamentos (T): leite integral (1); leite integral com óleo de soja (2); leite integral e zeranol (3); leite integral com óleo de soja e zeranol (4); colostro fermentado (5); colostro ...
Castro A.L.M.   +4 more
doaj  

Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells

open access: yesAdvanced Science, EarlyView.
Engineered through structure‐guided protein engineering, enCas12j‐8 significantly enhances the editing efficiency of compact Cas12j‐8 while maintaining high specificity. It enables efficient multiplexed genome editing and base editing using a single crRNA array, demonstrating broad applicability and therapeutic potential in genome engineering ...
Ru Meng   +14 more
wiley   +1 more source

Avaliação da digestibilidade de nutrientes, em bovinos, de alguns alimentos concentrados pela técnica de três estádios Evaluation of intestinal digestibility of different concentrate feeds using an in vitro three-step enzymatic procedure

open access: yesRevista Brasileira de Zootecnia, 2007
Este trabalho foi realizado com o objetivo de determinar a digestibilidade de componentes nutricionais não-degradados no rúmen por meio da técnica de três estádios.
Fernando Henrique Brussi Beran   +7 more
doaj   +1 more source

The relevance of specific csfs for stakeholders during ERP implementation: an empirical study from Oman [PDF]

open access: yes, 2013
The success of ERP systems implementation is affected by the extent to which stakeholders have been prepared for the project activities and its outcomes.
Al-Hinai, H   +2 more
core   +1 more source

Genomic Variation Underpins Genetic Divergence and Differing Salt Resilience in Sesbania bispinosa

open access: yesAdvanced Science, EarlyView.
Sesbania, a leguminous halophyte, thrives in saline soils. Comparative genomics reveals key genomic variations—particularly chromosomal inversions—are identified as contributors to population differentiation and salt resilience. These findings advance the understanding of genomic variation driving evolution and phenotypic differentiation and offer ...
Gai Huang   +13 more
wiley   +1 more source

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