Results 91 to 100 of about 1,535,898 (372)

Lower Limb Radiology of Distal Myopathy due to the S60F Myotilin Mutation [PDF]

, 2009
Distal myopathies are a clinically and genetically heterogenous group of disorders in which the distal limb musculature is selectively or disproportionately affected.
Birchall, Daniel, Chinnery, Patrick F., Goldfarb, Lev, Lochmueller, Hanns, McNeill, Alisdair, Reilich, Peter, Schramm, Nicolai, Straub, Volker, Walter, Maggie C.   +8 more
core   +1 more source

Altered Relaxation and Mitochondria‐Endoplasmic Reticulum Contacts Precede Major (Mal)Adaptations in Aging Skeletal Muscle and Are Prevented by Exercise

Aging Cell, EarlyView.
Slowed relaxation and altered MERCs embody early stages of aging in muscle, and are prevented by regular exercise. ABSTRACT Sarcopenia, or age‐related muscle dysfunction, contributes to morbidity and mortality. Besides decreases in muscle force, sarcopenia is associated with atrophy and fast‐to‐slow fiber type switching, which is typically secondary to
Ryan J. Allen, Ana Kronemberger, Qian Shi, R. Marshall Pope, Elizabeth Cuadra‐Muñoz, Wangkuk Son, Long‐Sheng Song, Ethan J. Anderson, Renata O. Pereira, Vitor A. Lira   +9 more
wiley   +1 more source

Transcriptomic Profiling Reveals Differences in Slow‐Twitch and Fast‐Twitch Muscles of a Cigarette Smoke‐Exposed Rat Model

Journal of Cachexia, Sarcopenia and Muscle
Background Cigarette smoking is known to affect muscle function and exercise capacity, including muscle fatigue resistance. Most studies showed diminished cross‐sectional area and fibre type shifting in slow‐twitch muscles such as the soleus, while ...
Timothy K. H. Fung, Kwok Kuen Cheung, Xia Wang, Benson W. M. Lau, Shirley P. C. Ngai   +4 more
doaj   +1 more source

Acute and chronic changes in rat soleus muscle after high‐fat high‐sucrose diet

Physiological Reports, 2017
The effects of obesity on different musculoskeletal tissues are not well understood. The glycolytic quadriceps muscles are compromised with obesity, but due to its high oxidative capacity, the soleus muscle may be protected against obesity‐induced muscle
Kelsey H. Collins, David A. Hart, Ian C. Smith, Anthony M. Issler, Raylene A. Reimer, Ruth A. Seerattan, Jaqueline L. Rios, Walter Herzog   +7 more
doaj   +1 more source

Forced Running Endurance Is Influenced by Gene(s) on Mouse Chromosome 10 [PDF]

, 2017
Acknowledgments The authors wish to acknowledge technical assistance from Mrs. Indrė Libnickienė and intellectual input from Dr. David A. Blizard. This research was funded by the European Social Fund under the Global Grant measure. Grant VP1-3.1-ŠMM-07-K-
Fokin, Andrej, Kvedaras, Mindaugas, Lionikas, Arimantas, Minderis, Petras, Ratkevicius, Aivaras, Venckunas, Tomas   +5 more
core   +1 more source

Transcriptional Diversity in Response to Aging Across Skeletal Muscles

Aging Cell, EarlyView.
We constructed transcriptional maps of 11 skeletal muscles from young and old mice, revealing age‐related tissue‐specific gene expression changes. Our findings highlight cellular composition shifts and new cell states in aged muscles, providing insights into muscle aging and potential therapeutic targets for age‐related muscle disorders. ABSTRACT Aging
Can Liu, Dongbin Zheng, Rui Zhang, Hong Li, Xingyan Tong, Yujie Wu, Geng Zhang, Siyuan Wang, Hongyu Chen, Zhinong Ren, Ying Sun, Chengdong Wang, Desheng Li, Xuewei Li, Mingzhou Li, Long Jin   +15 more
wiley   +1 more source

Role of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles [PDF]

, 2016
We exploited a variety of mouse models to assess the roles of JP45-CASQ1 (CASQ, calsequestrin) and JP45-CASQ2 on calcium entry in slow twitch muscles.
Bergamelli, Leda, Bongianino, Rossana, De Negri, Marco, Eckhardt, Jan, Mosca, Barbara, Priori, Silvia G., Protasi, Feliciano, Treves, Susan, Zorzato, Francesco   +8 more
core   +1 more source

Rapamycin Does Not Compromise Exercise‐Induced Muscular Adaptations in Female Mice

Aging Cell, EarlyView.
Rapamycin is largely compatible with the physical and skeletal muscle benefits of progressive weighted wheel running (PoWeR). The detrimental effects of rapamycin on glucose metabolism in the context of voluntary exercise are mitigated by intermittent dosing.
Christian J. Elliehausen, Szczepan S. Olszewski, Dennis M. Minton, Carolyn G. Shult, Aditya R. Ailiani, Michaela E. Trautman, Reji Babygirija, Dudley W. Lamming, Troy A. Hornberger, Adam R. Konopka   +9 more
wiley   +1 more source

Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]

, 2015
Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa, Megighian, Aram, Montecucco, Cesare, Pirazzini, Marco, Rigoni, Michela, Scorzeto, M., Zanetti, Giulia   +6 more
core   +2 more sources

Cortical output to fast and slow muscles of the ankle in the rhesus macaque.

Frontiers in Neural Circuits, 2013
The cortical control of fast and slow muscles of the ankle has been the subject of numerous reports yielding conflicting results. Although it is generally agreed that cortical stimulation yields short latency facilitation of fast muscles, the effects on
Heather M. Hudson, Darcy M. Griffin, Abderraouf eBelhaj-Saïf, Paul David Cheney   +3 more
doaj   +1 more source