Results 101 to 110 of about 67,049 (357)

Losartan treatment attenuates hindlimb unloading-induced atrophy in the soleus muscle of female rats via canonical TGF-β signaling [PDF]

, 2022
Toshinori Yoshihara, Mizuki Takaragawa, Shohei Dobashi, Hisashi Naıto   +3 more
openalex   +1 more source

Dual action of imeglimin on insulin secretion and sensitivity in type 2 diabetes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Imeglimin is a novel oral hypoglycemic agent approved for the treatment of type 2 diabetes in Japan, with dual actions to enhance insulin secretion and improve insulin sensitivity, suggested by preclinical evidence. However, the effect of imeglimin on tissue‐specific insulin sensitivity and glucose kinetics using glucose tracers is ...
Tsubasa Tajima, Hideyoshi Kaga, Naoaki Ito, Toshiki Kogai, Hitoshi Naito, Saori Kakehi, Satoshi Kadowaki, Yuya Nishida, Ryuzo Kawamori, Yoshifumi Tamura, Hirotaka Watada   +10 more
wiley   +1 more source

Effect of L-Arginine on Titin Expression in Rat Soleus Muscle After Hindlimb Unloading

Frontiers in Physiology, 2019
Nitric oxide (NO), produced by NO-synthases via L-arginine oxidation, is an essential trigger for signaling processes involved in structural and metabolic changes in muscle fibers.
Anna Ulanova, Anna Ulanova, Yuliya Gritsyna, Nikolai Salmov, Yuliya Lomonosova, Svetlana Belova, Tatyana Nemirovskaya, Boris Shenkman, Ivan Vikhlyantsev   +8 more
doaj   +1 more source

Low Cell pH Depresses Peak Power in Rat Skeletal Muscle Fibres at Both 30°C and 15°C: Implications for Muscle Fatigue [PDF]

, 2006
Historically, an increase in intracellular H+ (decrease in cell pH) was thought to contribute to muscle fatigue by direct inhibition of the cross-bridge leading to a reduction in velocity and force.
Adams, Bottinelli, Chase, Cooke, Debold, Debold, Donaldson, Fabiato, Fabiato, Fabiato, Fitts, Giulian, Hermansen, Hill, Knuth, Metzger, Metzger, Metzger, Metzger, Metzger, Pate, Ranatunga, Sahlin, Seow, Thompson, Umazume, Westerblad, Widrick, Widrick, Widrick, Wiseman, Zhao   +31 more
core   +3 more sources

Architecture of lower leg muscles in children: Reference curves and potential mechanisms of growth

Journal of Anatomy, EarlyView.
Muscle architecture (physiological cross‐sectional area, fascicle lengths and pennation angle) was measured from multimodal MRI scans of the lower legs of 197 children aged ≤15 years. We showed that lower leg muscle volumes (product of PCSA and fascicle length) increase primarily through increases in PCSA (transverse growth) rather than increases in ...
Brian V. Y. Chow, Suzanne Davies, Catherine Morgan, Caroline D. Rae, David I. Warton, Iona Novak, Ann Lancaster, Gordana C. Popovic, Rodrigo R. N. Rizzo, Claudia Y. Rizzo, Iain K. Ball, Robert D. Herbert, Bart Bolsterlee   +12 more
wiley   +1 more source

Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analyses [PDF]

, 2012
Peer reviewedPublisher ...
Blizard, David A, Carroll, Andrew M, Derry, Jonathan M J, Lionikas, Arimantas, Meharg, Caroline, Ratkevicius, Aivaras, Vandenbergh, David J   +6 more
core   +2 more sources

MRI‐based, 3D analysis of Achilles tendon longitudinal strain under passive loading reveals limitations in conventional 2D measurement

Journal of Anatomy, EarlyView.
Graphical overview of 2D and 3D length measurements of the free Achilles tendon. The figure also illustrates how the typical distal morphology of the soleus muscle affects 2D measurement. Abstract Quantifying strain in the free Achilles tendon (ATF) is essential for understanding its mechanical function, yet existing in vivo studies report inconsistent
Dongyu Deng, Hiroto Shiotani, Yasuo Kawakami   +2 more
wiley   +1 more source

Possible role of non-muscle alpha-actinins in muscle cell mechanosensitivity.

PLoS ONE, 2014
UnlabelledThe main hypothesis suggested that changes in the external mechanical load would lead to different deformations of the submembranous cytoskeleton and, as a result, dissociation of different proteins from its structure (induced by increased ...
Irina V Ogneva, Nikolay S Biryukov, Toomas A Leinsoo, Irina M Larina   +3 more
doaj   +1 more source

Photobiomodulation and platelet‐rich fibrin in the gastrocnemius muscle submitted to calcaneal tendinopathy in rats

Photochemistry and Photobiology, EarlyView.
The study evaluated different treatments for calcaneal tendinopathy in rats, focusing on the gastrocnemius muscle. Photobiomodulation (PBM), advanced platelet‐rich fibrin (A‐PRF), and their combination were tested. Treated animals showed improved muscle strength between 7 and 21 days, but without significant recovery of muscle fibers.
Pâmela Andressa Pauletto, Caroline Hammerschmitt Eduardo Schmitt, Fransael Franklyn Araújo da Silva, Maria Eduarda Luckner, Lucinéia de Fátima Chasko Ribeiro, Márcia Miranda Torrejais, Gladson Ricardo Flor Bertolini   +6 more
wiley   +1 more source

Disuse‐induced muscle‐type specific alterations and adiponectin pathway response in male mice

Physiological Reports
Disuse‐mediated Muscle Atrophy (DMA) causes persistent muscle weakness, limiting exercise training as a treatment. Adiponectin (ApN) emerged as a therapeutic candidate for muscle disorders.
Szczepanski Sébastien, Limpens Maëlle, Jenart Vincianne, Declèves Anne‐Emilie, Legrand Alexandre, Tassin Alexandra   +5 more
doaj   +1 more source