Results 111 to 120 of about 62,363 (313)
Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]
, 2015 Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa +6 more
core +2 more sources
Experimental Physiology, EarlyView.Abstract In activities of daily living, people walk at different speeds with or without carrying additional loads. In this study, we sought to examine how human adults manage these commonly encountered additional demands during walking. We measured electromyography (EMG), triceps surae H‐reflexes, joint motion and ground reaction forces (GRF) while ...
Bridgette A. P. Damewood +2 more
wiley +1 more source
Ecdysteroids: A novel class of anabolic agents? [PDF]
, 2015 Increasing numbers of dietary supplements with ecdysteroids are marketed as “natural anabolic agents”. Results of recent studies suggested that their anabolic effect is mediated by estrogen receptor (ER) binding. Within this study the anabolic potency of
BOTRE', Francesco +5 more
core +2 more sources
The multifaceted roles of ketones in physiology
Experimental Physiology, EarlyView.Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili +3 more
wiley +1 more source
Physiological Reports, 2020 Calcineurin is a Ca2+‐dependent serine/threonine phosphatase that dephosphorylates nuclear factor of activated T cells (NFAT), allowing for NFAT entry into the nucleus.
Kennedy C. Whitley +8 more
doaj +1 more source
Possible mechanism for changes in glycogen metabolism in unloaded soleus muscle [PDF]
Carbohydrate metabolism has been shown to be affected in a number of ways by different models of hypokinesia. In vivo glycogen levels in the soleus muscle are known to be increased by short-term denervation and harness suspension.
Henriksen, E. J., Tischler, M. E.
core +1 more source
Nitric oxide regulates skeletal muscle fatigue, fiber type, microtubule organization, and mitochondrial ATP synthesis efficiency through cGMP-dependent mechanisms [PDF]
, 2016 Aim: Skeletal muscle nitric oxide–cyclic guanosine monophosphate (NO-cGMP) pathways are impaired in Duchenne and Becker muscular dystrophy partly because of reduced nNOSμ and soluble guanylate cyclase (GC) activity.
Balke, Jordan E +8 more
core +1 more source
The evolution of muscle spindles
Experimental Physiology, EarlyView.Abstract Muscle spindles are stretch‐sensitive mechanoreceptors found in the skeletal muscles of most four‐limbed vertebrates. They are unique amongst sensory receptors in the ability to regulate their sensitivity by contraction of the intrafusal muscle fibres on which the sensory endings lie.
Robert W. Banks, Uwe Proske
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti +6 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 2010 Angiotensin-converting enzymes 1 (ACE1) and 2 (ACE2) are key enzymes of the renin-angiotensin system, which act antagonistically to regulate the levels of angiotensin II (Ang II) and Ang-(1-7).
T. Fernandes +2 more
doaj