Results 261 to 270 of about 1,535,898 (372)

Changes in total fiber numbers of disused soleus muscle on rats.

open access: bronze, 1990
Y Nakagawa   +4 more
openalex   +2 more sources

Deletion of Skeletal Muscle Mitochondrial Glutamic‐Oxaloacetic Transaminase (GOT2) Enhances Oxaloacetate Inhibition of Succinate Dehydrogenase and Alters Substrate Selectivity

open access: yesThe FASEB Journal, Volume 39, Issue 14, 31 July 2025.
Oxaloacetate is centrally positioned in the TCA cycle to regulate critical metabolic steps. Deletion of mitochondrial glutamic‐oxaloacetic transaminase (GOT2) increases oxaloacetate accumulation and inhibits succinate dehydrogenase (SDH or complex II).
Brian D. Fink   +3 more
wiley   +1 more source

Aging and Altered Gravity: A Cellular Perspective

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
We propose that, unlike biological aging, where Primary hallmarks initiate damage, spaceflight may trigger a feedback loop between Antagonistic and Integrative hallmarks, driving accelerated aging. Returning to 1 g restores proper signaling and breaks the cycle.
Sharon van Rijthoven   +1 more
wiley   +1 more source

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