Results 271 to 280 of about 67,049 (357)

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun   +16 more
wiley   +1 more source

HUWE1 in Skeletal Muscle Prevents Muscle Fatigue via Maintaining Iron and Calcium Homeostasis

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
This study investigates the impact of iron homeostasis on exercise. Loss of the HECT domain‐containing ubiquitin ligase E3 (HUWE1) in skeletal muscle restrains the exercise performance in mice with downregulated ferroportin expression leading to iron overload, which is ameliorated by dietary iron restriction.
Huike Jiao   +10 more
wiley   +1 more source

Treatment with ActRIIB-mFc Produces Myofiber Growth and Improves Lifespan in the \u3cem\u3eActa1\u3c/em\u3e H40Y Murine Model of Nemaline Myopathy [PDF]

open access: yes, 2016
Allen, Kenneth P.   +11 more
core   +1 more source

Nobiletin Ameliorates Skeletal Muscle Performance in D‐Galactose‐Induced Aging Mice by Boosting Aerobic Metabolism

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
Nob improved muscle function and prevented muscle atrophy in D‐gal‐induced aging mice. Nob enhanced the aerobic metabolism of myofibers in D‐gal‐induced aging mice. Nob activated the SIRT1/PGC1α/Nrf2 pathway, enhancing muscle metabolism and function. ABSTRACT The decrease in muscle performance during aging will not only lead to challenges in movement ...
Huihui Wang   +6 more
wiley   +1 more source

Reconstruction of Skin Defects of the Lower Leg Using a Soleus Muscle Flap Transposition.

open access: diamond, 1997
Yasunobu HIBI   +3 more
openalex   +1 more source

Mitigating Dexamethasone‐Induced Muscle Wasting and Mitochondrial Impairment in Mice on a High‐Fat and High‐Sucrose Diet With Peanut Sprout Extract

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
Peanut sprout extract (PSE) significantly attenuated skeletal muscle atrophy induced by a high‐fat, high‐sucrose diet and dexamethasone, improving muscle strength and reducing triglyceride accumulation and inflammation. It enhanced mitochondrial function by upregulating TFAM and OXPHOS proteins and partially restoring PGC1α expression.
Sang‐Mi Jo   +4 more
wiley   +1 more source

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