Results 51 to 60 of about 1,535,898 (372)

Resistance exercise reduced the expression of fibroblast growth factor-2 in skeletal muscle of aged mice

Integrative Medicine Research, 2016
Background: Fibroblast growth factor-2 (FGF-2) protein level has been shown to be elevated in aged mice muscle compared to adult mice. It activates the satellite cell quiescence, which leads to satellite cell depletion and may accelerate aging process ...
Jin-Soo Kim, Dong Hyun Yoon, Hee-jae Kim, Mi-jung Choi, Wook Song   +4 more
doaj   +1 more source

Acute bout of exercise downregulates thioredoxin‐interacting protein expression in rat contracting skeletal muscles

Physiological Reports, 2020
We previously reported that in rat skeletal muscle, disuse (i.e., decreased muscle contractile activity) rapidly increases thioredoxin‐interacting protein (TXNIP), which is implicated in the reduced glucose uptake.
Song‐Gyu Ra, Emi Kawamoto, Keiichi Koshinaka, Maiko Iwabe, Yuki Tomiga, Hiroki Iizawa, Hiroki Honda, Yasuki Higaki, Kentaro Kawanaka   +8 more
doaj   +1 more source

Two weeks of metformin treatment induces AMPK-dependent enhancement of insulin-stimulated glucose uptake in mouse soleus muscle.

American Journal of Physiology. Endocrinology and Metabolism, 2014
Metformin-induced activation of the 5'-AMP-activated protein kinase (AMPK) has been associated with enhanced glucose uptake in skeletal muscle, but so far no direct causality has been examined.
Jonas M Kristensen, J. T. Treebak, P. Schjerling, L. Goodyear, J. Wojtaszewski   +4 more
semanticscholar   +1 more source

Pancreatic Cancer‐Derived Extracellular Vesicles Enriched with miR‐223‐5p Promote Skeletal Muscle Wasting Associated with Cachexia

Advanced Science, EarlyView.
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu, Rongxi Shen, Li Zhang, Xuejin Gao, Xinbo Wang, Changhua Zhang, Xi Chen, Xinying Wang   +7 more
wiley   +1 more source

Ishophloroglucin A, Isolated from Ishige okamurae, Alleviates Dexamethasone-Induced Muscle Atrophy through Muscle Protein Metabolism In Vivo

Marine Drugs, 2022
The in vitro capacity of Ishige okamurae extract (IO) to improve impaired muscle function has been previously examined. However, the mechanism underlying IO-mediated muscle protein metabolism and the role of its component, Ishophloroglucin A (IPA), in ...
Hye-Won Yang, Seyeon Oh, Dong-Min Chung, Minyoung Seo, Shin Jae Park, You-Jin Jeon, Kyunghee Byun, BoMi Ryu   +7 more
doaj   +1 more source

Comparison of Capillary Architecture between Slow and Fast Muscles in Rats Using a Confocal Laser Scanning Microscope [PDF]

, 2010
The skeletal muscle is classified into 2 types, slow oxidative or fast glycolytic muscle. For further characterization, we investigated the capillary architecture in slow and fast muscles.
Fujino, Hidemi, Kumagishi, Kanae, Momota, Ryusuke, Murakami, Shinichiro, Ohtsuka, Aiji, Takeda, Isao   +5 more
core   +1 more source

Subthalamic Electrophysiological Mapping of Gait Initiation Dynamics and Freezing in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective The objective of this study was to investigate the relationships among subthalamic nucleus (STN) activity, gait initiation (GI), and freezing of gait (FOG) in patients with Parkinson's disease (PD). Methods We recorded GI and STN local field potentials (LFPs) via externalized cables in 38 patients with PD (35 reporting FOG in daily life ...
Antoine Collomb‐Clerc, Mathieu Yeche, Adèle Demain, Angèle Van Hamme, Claire Olivier, Hayat Belaid, Déborah Ziri, Stéphane Derrey, Sara Fernandez‐Vidal, Katia Lehongre, Carine Karachi, Brian Lau, Marie‐Laure Welter   +12 more
wiley   +1 more source

Electrical stimulated GLUT4 signalling attenuates critical illness‐associated muscle wasting

Journal of Cachexia, Sarcopenia and Muscle, 2022
Background Critical illness myopathy (CIM) is a debilitating condition characterized by the preferential loss of the motor protein myosin. CIM is a by‐product of critical care, attributed to impaired recovery, long‐term complications, and mortality.
Alex B. Addinsall, Nicola Cacciani, Anders Backéus, Yvette Hedström, Ganna Shevchenko, Jonas Bergquist, Lars Larsson   +6 more
doaj   +1 more source

Parallel Facilitatory Reflex Pathways from the Foot and Hip to Flexors and Extensors in the Injured Human Spinal Cord [PDF]

, 2007
Spinal integration of sensory signals associated with hip position, muscle loading, and cutaneous sensation of the foot contributes to movement regulation.
Kay, Elizabeth, Knikou, Maria, Schmit, Brian D.   +2 more
core   +2 more sources

Effects of the Dietary Supplement 5α‐Hydroxy‐Laxogenin in the Orchiectomized Rat Model

Drug Testing and Analysis, EarlyView.
The dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated in the castrated male rat for potential androgenic and anabolic effects. Moreover, androgen receptor binding of 5α‐hydroxy‐laxogenin was modelled by in silico docking. While molecular modelling supports androgen receptor binding, we observed neither androgenic nor anabolic effects ...
Daniel Derwand, Oliver Zierau, Clemens Alexander Wolf, Gerhard Wolber, Annekathrin Martina Keiler   +4 more
wiley   +1 more source