Results 61 to 70 of about 62,363 (313)
Biomedicines, 2023 We have developed DNA aptamers that can inhibit the toxic effects of advanced glycation end products (AGE-Apts). We herein evaluated the effects of AGE-Apts on muscle mass and strength in senescence-accelerated mouse prone 8 (SAMP8) mice. Eight-month-old
Yusaku Mori +11 more
doaj +1 more source
An isovelocity dynamometer method to determine monoarticular and biarticular muscle parameters [PDF]
, 2012 This study aimed to determine whether subject-specific individual muscle models for the ankle plantar flexors could be obtained from single joint isometric and isovelocity maximum torque measurements in combination with a model of plantar flexion ...
Conceição, F +4 more
core +1 more source
Reinnervation and regeneration of denervated rat soleus muscles [PDF]
Muscle & Nerve, 1997 Muscle atrophy is a serious and sometimes irreversExperiments were approved by the University Committee on Use and Care of Animals. ible consequence of peripheral nerve damage.4 Recently, we found that muscle atrophy is reversible to Four groups of denervated muscles were used in this study.
Lynn Billington, Lynn Billington
openaire +3 more sources
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.Abstract Quantitative model‐based clinical trial simulation tools play a critical role in informing study designs through simulation before actual execution. These tools help drug developers explore various trial scenarios in silico to select a clinical trial design to detect therapeutic effects more efficiently, therefore reducing time, expense, and ...
Jongjin Kim +10 more
wiley +1 more source
Atrophy, oxidative switching and ultrastructural defects in skeletal muscle of the ataxia telangiectasia mouse model [PDF]
, 2019 Ataxia telangiectasia is a rare, multi system disease caused by ATM kinase deficiency. Atm-knockout mice recapitulate premature aging, immunodeficiency, cancer predisposition, growth retardation and motor defects, but not cerebellar neurodegeneration and
Aguanno, Salvatore +8 more
core +1 more source
Myonuclear loss in atrophied soleus muscle fibers [PDF]
The Anatomical Record, 1997 A skeletal muscle fiber consists of many successive "territories," each controlled by the nucleus residing in that territory. Because nuclei appear to control a specific amount of territory (nuclear domain), nuclei must be added to accommodate an increase in fiber size.
Sharon van Nostran +8 more
openaire +2 more sources
Aging Cell, Volume 24, Issue 4, April 2025.In females, estradiol deficiency is a major environmental factor contributing to the age‐associated effects on satellite cells. To assess cell‐intrinsic versus environmental regulation of satellite cells, we perform two transplantation experiments, Adult or Aged satellite cells transplanted into Adult recipients, and Adult satellite cells transplanted ...
Brian P. Sullivan +7 more
wiley +1 more source
Effect of passive stretching on the immobilized soleus muscle fiber morphology
Brazilian Journal of Medical and Biological Research, 2004 The aim of the present study was to determine the effect of stretching applied every 3 days to the soleus muscle immobilized in the shortened position on muscle fiber morphology. Eighteen 16-week-old Wistar rats were used and divided into three groups of
Coutinho E.L. +4 more
doaj
Short-term creatine supplementation changes protein metabolism signaling in hindlimb suspension
Brazilian Journal of Medical and Biological ResearchThe effect of a short-term creatine supplementation on hindlimb suspension (HS)-induced muscle atrophy was investigated. Creatine monohydrate (5 g/kg b.w. per day) or placebo, divided in 2 daily doses, was given by oral gavage for 5 days.
G.N. Marzuca-Nassr +7 more
doaj +1 more source
Sports, 2023 The purpose of this study was to investigate the effects of 4 weeks of soleus stretching on ankle flexibility and dynamic balance, as well as selected monitoring and performance tests in soccer.
Mohammad Alimoradi +4 more
doaj +1 more source