Results 101 to 110 of about 10,324 (277)

DNA Nanoarray for Multiplexed RNA Detection With Single‐Molecule Readout

Advanced Science, EarlyView.
A carrier‐based DNA nanoarray integrates programmable nucleic acid hybridization with solid‐state nanopore readout for direct RNA detection at single‐molecule resolution. A ternary encoding system enables 27 carriers with 81 addressable sensing sites, allowing the simultaneous identification of targets spanning a wide size range, from short microRNAs ...
Yunxuan Li, Yesheng Wang, Chunmiao Yu, Siyu Hou, Elli Mylona, Plamena Naydenova, Jingyuan Zhao, Hong Yuan, Jingsong Duan, Hendrik F. P. Runge, Stephen Baker, Jinbo Zhu, Ulrich F. Keyser   +12 more
wiley   +1 more source

Intrusion of polyethylene glycol into solid-state nanopores

RSC Advances, 2018
The mechanism of PEG molecule penetration into nanopores upon mechanical pressure is understood.
Yueting Sun, Chengliang Xu, Yibing Li
openaire   +3 more sources

N‐Doping Activated Presodiation Enhances Sodium‐Ion Provision in Hard Carbon Anodes

Advanced Science, EarlyView.
Introducing pyrrolic‐N sites enables efficient presodiation and stronger PF6− capture, thus pre ‐ forming a robust inorganic‐rich SEI layer in hard carbon anodes. ABSTRACT Hard carbon (HC) is considered the most promising anode material for commercial sodium‐ion batteries (SIBs), yet it still faces critical challenges such as low initial Coulombic ...
Hua Lin, Wenxing Miao, Yanrong Shi, Guangyi Mao, Ding Ding, Jian Weng, Zhongxiong Fan, Qingchi Xu, Jun Xu   +8 more
wiley   +1 more source

Single-Molecule Bonds Characterized by Solid-State Nanopore Force Spectroscopy [PDF]

, 2016
Weak molecular interactions drive processes at the core of living systems, such as enzyme−substrate interactions, receptor−ligand binding, and nucleic acid replication. Single-molecule force spectroscopy is a remarkable tool for revealing molecular scale
Andre Marziali (184695), Dhruti Trivedi (2342356), Vincent Tabard-Cossa (541153), Nahid N. Jetha (279383), Matthew Wiggin (2342359), Jason R. Dwyer (1774480)   +5 more
core   +1 more source

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Advanced Science, EarlyView.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao   +12 more
wiley   +1 more source

Solid-State Nanopore for Detecting Individual Biopolymers [PDF]

, 2009
Solid-state nanopores have been fabricated and used to characterize single DNA and protein molecules. Here we describe the details on how these nanopores were fabricated and characterized, the nanopore sensing system setup, and protocols of using these nanopores to characterize DNA and protein molecules.
Jiali, Li, Jene A, Golovchenko
openaire   +2 more sources

Low-cost solid state nanopore biosensing technology towards early disease detection [PDF]

, 2020
Solid-state nanopore based biosensors are cost effective, high-throughput engines for single molecule detection of biomolecules, which is useful for detecting epigenetic modifications on DNA; one of these being the potentially cancerous hypo, or ...
Bello, Julian
core   +1 more source

Slowing Down DNA Translocation Through Solid-State Nanopores by Pressure [PDF]

, 2013
The effect of applied pressure on event duration distributions in 3 kb dsDNA translocation is systematically investigated. The effects of pressure magnitude and nanopore size on the length discrimination between 615 bp and 1.14 kbp dsDNA is studied.
Hengbin Zhang, Qingtao Li, Dapeng Yu, Zhao, Qing, Zhipeng Tang, Tang, Zhipeng, Zhang, Hengbin, Liu, Song, Yu, Dapeng, Yang, Fuhua, Song Liu, Zhongchao Fan, You, Liping, Qing Zhao, Fan, Zhongchao, Liping You, Zhang, Jingmin, Xuemei Li, Li, Qingtao, Jingmin Zhang, Fuhua Yang, Li, Xuemei   +21 more
core   +1 more source

Impedance of Nonelectroneutral Solid Electrolyte Interphases With Nanopores: A Theoretical Model

Advanced Science, EarlyView.
Physical modeling reveals that often‐neglected non‐electroneutrality and nanopores in the solid‐electrolyte interphase (SEI) govern the impedance behavior. Under nonreactive conditions, the low‐frequency constant‐phase element (CPE) phenomenon can be attributed to the nonelectroneutral local conditions in the SEI.
Chenkun Li, Jun Huang
wiley   +1 more source

Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor

Nature Communications, 2018
Involved in various diseases, hyaluronic acid is an important indicator of pathophysiology. Here, the authors report on a solid-state nanopore for the detection of the molecular weight and abundance of hyaluronic acid and demonstrate the system by ...
Felipe Rivas, Osama K. Zahid, Heidi L. Reesink, Bridgette T. Peal, Alan J. Nixon, Paul L. DeAngelis, Aleksander Skardal, Elaheh Rahbar, Adam R. Hall   +8 more
doaj   +1 more source