Results 201 to 210 of about 7,329 (254)

Pitfalls and missing links in current understanding of 4D genomes

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley   +1 more source

Multiple consecutive recapture of rigid nanoparticles using a solid-state nanopore sensor. [PDF]

Electrophoresis, 2018
Lee JS, Peng B, Sabuncu AC, Nam S, Ahn C, Kim MJ, Kim M.   +6 more
europepmc   +1 more source

Intraparticular Heterogeneity Limits Capacity in Lithium–Sulfur Batteries With Carbonate Electrolyte

Battery Energy, Volume 5, Issue 3, May 2026.
Cryo‐electron‐microscopy and electrochemical testing reveal that the cathode‐electrolyte interphase in Li–S batteries with carbonate electrolytes forms heterogeneously across carbon particles. This intraparticle heterogeneity limits capacity and rate performance, highlighting the critical role of particle size and cathode‐electrolyte interphase ...
Ayca Senol Gungor, Jean‐Marc von Mentlen, Francisco Javier García‐Soriano, Christian Zaubitzer, Milivoj Plodinec, Jean G. A. Ruthes, Sven Dunkel, Volker Presser, Alen Vizintin, Vanessa Wood, Christian Prehal   +10 more
wiley   +1 more source

A critical review of porous adsorbents for air separation: From fundamental insights to rational adsorbent design

AIChE Journal, Volume 72, Issue 4, April 2026.
Abstract Air separation via selective adsorption using porous adsorbents offers energy‐efficient alternatives to cryogenic distillation for producing high‐purity O2 and N2. Adsorbent efficacy depends on balancing selectivity, durability, and performance consistency across varying conditions. This comprehensive review critically discusses the design and
Tianqi Wang, Daisong Chen, Tianyi Zhang, Boyu Zhang, Ruiqiang Wang, Zhengdong Liu, Mei Hong, Youssef Belmabkhout, Qinfen Gu, Jin Shang   +9 more
wiley   +1 more source

Large‐Scale Hydrogen Storage: Surface and Subsurface Challenges

ChemBioEng Reviews, Volume 13, Issue 2, April 2026.
This review examines underground hydrogen storage with emphasis on the interaction between surface facilities and subsurface reservoirs. Variable renewable hydrogen requires compression, buffering, and purification before injection, while subsurface processes influence wellhead pressure, temperature, and composition.
Mostafa Montazeri, Alireza Salmachi, Manouchehr Haghighi, Tara Hosseini   +3 more
wiley   +1 more source

Review of recent advances in the design, synthesis, and modification of biochar for remediation of heavy metal pollution in water

The Canadian Journal of Chemical Engineering, Volume 104, Issue 4, Page 1769-1795, April 2026.
Research frontiers in using biochar for heavy metal remediation. Abstract Heavy metal contamination of water has long been a serious environmental issue. Biochar and biochar‐based composites are emerging as effective and sustainable solutions for heavy metal removal due to their strong adsorption abilities and environmentally friendly nature.
Soumik Chakma, Mehedi Hasan, Sudip K. Rakshit, Janusz Kozinski, Kang Kang   +4 more
wiley   +1 more source

Small and Large Extracellular Vesicles in Circulation of Diffuse Large B‐Cell Lymphoma Patients Originate From Different Cell Types of the Tumor Microenvironment

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Malignant and non‐malignant cells within the tumor microenvironment (TME) actively secrete extracellular vesicles (EVs) that may mediate intercellular communication or enter the blood stream. Circulating EVs in Diffuse Large B‐Cell Lymphoma (DLBCL) patients are a promising source of liquid biopsy biomarkers; however, whether different cellular
Filippo Maltoni, Steven Wang, Mischa. F. B. Steketee, Cristina A. Gómez‐Martín, Esther E. E. Drees, Federica Morelli, Leontien Bosch, Monique van Eijndhoven, Gert Jan Timmers, Ilse Houtenbos, Josée M. Zijlstra, Xiaofei Ye, Qiang Pan‐Hammarström, Martine E. D. Chamuleau, Pier Luigi Zinzani, Yongsoo Kim, Lucia Catani, Dirk Michiel Pegtel   +17 more
wiley   +1 more source

Non‐Viral Cytokine‐Inducible SH2 Containing Protein Locus‐Specific Integrated Fibroblast Activation Protein Alpha‐Targeting Chimeric Antigen Receptor T Cells Achieve Potent Antitumor Efficacy in Glioblastoma

MedComm, Volume 7, Issue 4, April 2026.
FAPα is a dual target on glioblastoma cells and perivascular cells. Using a high‐affinity anti‐FAPα nanobody, we generated CISH‐KO FAPα‐CAR‐T cells via non‐viral CRISPR–Cas9 integration. These cells demonstrated enhanced proliferation and superior antitumor efficacy in patient‐derived organoids and orthotopic mouse models compared to conventional CAR‐T
Xin Dong, Yao Sun, Yuetong Guo, Jiao Wang, Fei Wang, Ziming Wang, Ruizhen Li, Fei Xie, Tingting Tan, Baijie Cheng, Ronghan Huang, Shu Zhang, Xiaotong Lin, Zhaoze Guo, Hubing Wu, Hao Wu, Xubiao Zhang, Guozhu Xie   +17 more
wiley   +1 more source

Toxic mechanisms of amyloid oligomers and therapeutic strategies

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Amyloid oligomers are increasingly recognized as the major toxic contributors across protein‐misfolding disorders. In this review, we cover mechanistic evidence showing how these transient and structurally heterogeneous oligomers disrupt cellular homeostasis by: (i) permeabilizing lipid membranes and forming ion‐conducting pores; (ii ...
Magdalena I. Ivanova, Carmelo La Rosa, Ayyalusamy Ramamoorthy   +2 more
wiley   +1 more source

In vitro, cellular and in vivo studies of amyloid oligomers structure and toxicity: Challenges and advances

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Oligomeric assemblies of amyloidogenic proteins, such as Aβ, tau, α‐synuclein, amylin, transthyretin, and TDP‐43, are increasingly recognized as key drivers of cellular dysfunction across a range of neurodegenerative and systemic disorders.
Magdalena I. Ivanova, Carmelo La Rosa, Ayyalusamy Ramamoorthy   +2 more
wiley   +1 more source