Results 51 to 60 of about 20,246 (268)

Controlling Polymer Capture and Translocation by Electrostatic Polymer-Pore Interactions [PDF]

, 2017
Polymer translocation experiments typically involve anionic polyelectrolytes such as DNA molecules driven through negatively charged nanopores. Quantitative modelling of polymer capture to the nanopore followed by translocation therefore necessitates the
Abramowitz M., Risken H., Rowghanian P., Sahin Buyukdagli, T. Ala-Nissila   +4 more
core   +2 more sources

DNA Translocations through Solid-State Plasmonic Nanopores [PDF]

Nano Letters, 2014
Nanopores enable label-free detection and analysis of single biomolecules. Here, we investigate DNA translocations through a novel type of plasmonic nanopore based on a gold bowtie nanoantenna with a solid-state nanopore at the plasmonic hot spot.
Francesca Nicoli, Daniel Verschueren, Misha Klein, Cees Dekker, Magnus P. Jonsson   +4 more
openaire   +2 more sources

Digital immunoassay for biomarker concentration quantification using solid-state nanopores

Nature Communications, 2021
The concentration of a biomarker in solution can be determined by counting single molecules. Here the authors report a digital immunoassay scheme with solid-state nanopore readout to quantify a target protein and use this to measure thyroid-stimulating ...
Liqun He, Daniel R. Tessier, Kyle Briggs, Matthaios Tsangaris, Martin Charron, Erin M. McConnell, Dmytro Lomovtsev, Vincent Tabard-Cossa   +7 more
doaj   +1 more source

Localized Nanopore Fabrication via Controlled Breakdown

Nanomaterials, 2022
Nanopore sensors provide a unique platform to detect individual nucleic acids, proteins, and other biomolecules without the need for fluorescent labeling or chemical modifications.
Cuifeng Ying, Tianji Ma, Lei Xu, Mohsen Rahmani   +3 more
doaj   +1 more source

Monitoring Protein Adsorption with Solid-state Nanopores [PDF]

Journal of Visualized Experiments, 2011
Solid-state nanopores have been used to perform measurements at the single-molecule level to examine the local structure and flexibility of nucleic acids, the unfolding of proteins, and binding affinity of different ligands. By coupling these nanopores to the resistive-pulse technique, such measurements can be done under a wide variety of conditions ...
David J, Niedzwiecki, Liviu, Movileanu
openaire   +2 more sources

Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology

Advanced Engineering Materials, EarlyView.
We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham, Chenyu Wen, Mohammad Hadi Khaksaran, Won‐Yong Lee, Javier Cruz, Klas Hjort, Dongping Wu, Shi‐Li Zhang   +7 more
wiley   +1 more source

Low-Area Four-Channel Controlled Dielectric Breakdown System Design for Point-of-Care Applications

Sensors, 2022
In this study, we propose a low-area multi-channel controlled dielectric breakdown (CDB) system that simultaneously produces several nanopore sensors. Conventionally, solid-state nanopores are prepared by etching or drilling openings in a silicon nitride
Jonggi Hong, Yeonji Oh, Hojong Choi, Jungsuk Kim   +3 more
doaj   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Colloquium: Physical approaches to DNA sequencing and detection [PDF]

, 2008
With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, a revolutionary sequencing method is needed for the cost-effective and ...
Di Ventra, Massimiliano, Zwolak, Michael
core   +2 more sources

On‐Surface Indigo‐Based Bimolecular Coordination Networks with Programmable Regular or Vitreous Structure

Advanced Functional Materials, EarlyView.
A previously unreported coordination motif stabilising single Fe atoms by indigo chelation and pyridyl coordination on Au(111) has been revealed. By using planar tritopic pyridyl linkers (TPyB), extended 2D porous networks of indigo3(TPyB)2Fe6 form. These networks can be crystalline or vitreous and offer an environment where individual coordination ...
Hongxiang Xu, Ritam Chakraborty, Biao Yang, Dennis Meier, Joachim Reichert, Svetlana Klyatskaya, Mario Ruben, Shobhana Narasimhan, Johannes V. Barth, Anthoula C. Papageorgiou   +9 more
wiley   +1 more source